慢性淋巴细胞性甲状腺炎合并甲状腺结节的临床分析  

Clinical Study of Coexistent Chronic Lymphocytic Thyrioditis with Nodules

作　　者：王智强[1] 孔令宇[1] 聂春磊[1] 管强[1] 张杰武[1] 

机构地区：[1]哈尔滨医科大学附属肿瘤医院头颈外科甲状腺病区,黑龙江哈尔滨150081

出　　处：《现代生物医学进展》2012年第21期4054-4057,共4页Progress in Modern Biomedicine

摘　　要：目的:研究分析中国东北地区慢性淋巴细胞性甲状腺炎(CLT)合并甲状腺结节的诊断和治疗方式。方法:回顾性分析2009年9月--2010年12月收治经病理证实的CLT合并甲状腺结节的共151病例,依据不同的病理类型分组,就临床特点、诊断和治疗进行比较。结果:CLT合并甲状腺乳头状癌组共58例,女性51例,男性7例,平均年龄37.5±4岁,平均病程18个月,28例为腺体内单发结节,病灶平均直径为0.9±0.56 cm,36例病灶直径小于1.0 cm,42例见结节内伴钙化。CLT合并良性结节组98例,女性患者93例,男性患者5例,平均年龄48.1±9岁,平均病程72个月,34例为腺体内单发结节,病灶平均直径1.8±0.42 cm,35例病灶直径小于1.0 cm,10例见结节内伴钙化。两组在发病年龄、病程、结节个数及钙化方面的差异均有统计学意义。结论:CLT合并甲状腺癌微小癌多见,淋巴结转移率低,彩超提示单发结节或者结节合并钙化的病例,应行手术治疗。Objective： To investigate the principles of diagnosis and treatment of the patients who has chronic lymphocytic thy- roiditis （CLT） coexistent with nodules in northeast area of China. Methods： We retrospectively analysed the 151 cases of CLT concomi- tant with nodules from September 2009 to December 2010. A comparison of the clinical data including clinicopathologic features, treat- mentand prognosis was made between these groups by retrospective research. Results： The patients of CLT coexistent papillary thyroid carcinoma included 51 women and 7 men,with an average age of 37.5±4 years and symptoms duration of 18 months, and there were 28 cases of solitary nodule.The mean tumor size was 0.9± 0.56 cm, and 36 cases foei diameter 〈1.0 era, and 42 cases of calcification. The patients with benign nodules included 93 women and 5 men,with average age of 48.1±9 years symptoms duration of 72 months, and 34 cases of solitary nodule. The mean tumor size was 1.8±0.42 cm, and 35 cases foci diameter 〈1.0 era, and 10 cases of calcification. Age of onset, symptoms duration,nodule numbers and calcification in nodules had significant difference between these groups. Conclusion： The chronic lymphocytic thyroiditis coexist with thyroid carcinoma was mostly papillary thyroid microcarcinoma having a low rate lymph node metastasis. Surgical intervention should be considered with such conditions, including solitrary solid nodule and calcifi- cation revealed by ultrasonography.

关 键 词：慢性淋巴细胞性甲状腺炎 自身免疫性疾病 甲状腺结节 

分 类 号：R736.1[医药卫生—肿瘤]