羧酸及其衍生物的NaBH_4还原体系研究进展  

Progress on Reduction of Carboxylic Acid and Its Derivatives via the NaBH_4 System

作　　者：宋超[1] 何杰[1] 李杰[1] 付焱[1] 

机构地区：[1]河北医科大学药学院新药开发研究室,石家庄050017

出　　处：《化学通报》2012年第7期614-620,共7页Chemistry

基　　金：国家重点基础研究发展计划(2007CB512102)资助

摘　　要：NaBH4还原体系可以快速、高效、选择性地还原羧酸及其衍生物。本文介绍了8类NaBH4还原体系的最近研究成果。通过对各个还原体系的分析,讨论了各类还原体系的反应机理和反应条件,并比较了不同还原体系的还原能力和适用范围。The sodium borohydride system is a group of chemical reagents with rapid, effective and selective specificities in the reduction of earboxylic acid and its derivatives. In this paper, eight categories of sodium borohydride reduction system were introduced. The recent progress in the reaction mechanism and conditions, as well as the reduction capacity and application scope of the reduction system were reviewed.

关 键 词：硼氢化钠 还原反应 羧酸 羧酸衍生物 

分 类 号：O621.2[理学—有机化学]