磺基水杨酸修饰电极联吡啶钌电化学发光体系测定可待因的研究  

Determination of codeine based on a sulfosalicylic acid modified glassy carbon electrode using Ru(bpy)-3^(2+) electrochemiluminescence

作　　者：腊明[1] 陈昌东[1,2] 冯云晓[1] 蔡卓[2] 

机构地区：[1]平顶山学院,平顶山467000 [2]广西大学化学化工学院,南宁530000

出　　处：《分析试验室》2012年第8期70-73,共4页Chinese Journal of Analysis Laboratory

基　　金：河南省教育厅科学技术研究重点项目(12B430018);平顶山学院高层次人才科研启动基金资助

摘　　要：基于磷酸可待因对联吡啶钌在该电极上的电化学及其发光行为的增敏作用,建立了一种直接测定磷酸可待因的电化学发光新方法。在最佳实验条件下,磷酸可待因在1.0×10-4～4.0×10-6mol/L和4.0×10-6～2.0×10-7mol/L与相对发光强度呈线性关系,检出限为1.0×10-7mol/L(S/N=3)。连续测定4.0×10-7mol/l磷酸可待因5次,发光强度的RSD为2.7%。方法用于模拟尿样中磷酸可待因的测定,结果满意。Based on the enhancement of the electrochemical and ECL characteristics of Ru（bpy）32＋ in the presence of codeine,a new ECL method was established for the determination of codeine at the modified electrode（P-SSA/GC/CME） in this paper.Under the optimal experimental conditions,the ECL intensities increased linearly with the concentration of codeine in the ranges of 1.0×10-4～4.0×10-6 mol/L and 4.0×10-6～2.0×10-7 mol/L.The detection limit for codeine was 1.0×10-7 mol/L and the RSD for 5 times determination of 4.0×10-7 mol/l codeine was 2.7%.Codeine was successfully determined in the spiked human urine samples.

关 键 词：电致化学发光 联吡啶钌 磺基水杨酸 可待因 

分 类 号：O657.1[理学—分析化学]