脑出血早期血肿扩大的危险因素研究  

THE ANALYSIS OF RISK FACTORS INDUCING ENLARGEMENT OF HEMATOMA IN PATIENTS WITH INTRACEREBRAL HEMORRHAGE IN EARLY STAGE

作　　者：徐嘉贺[1] 凌文通[1] 

机构地区：[1]中山市人民医院,广东中山528403

出　　处：《现代医院》2012年第8期31-32,共2页Modern Hospitals

摘　　要：目的了解脑出血患者早期发生血肿范围扩大的相关危险因素。方法选择2009年6月～2010年12月期间,前往本院急诊并住院的200名脑出血患者,记录患者的基本信息和临床资料,并按照24 h后CT复查的结果按照血肿有无扩大将所有患者分为两组,运用单因素分析和多因素logistic回归寻找早期血肿扩大的危险因素。结果所有200名脑出血患者中,有54名患者发生了早期血肿扩大,总的发生率为27%;与无血肿扩大组比较,血肿扩大组平均动脉压较高,病程较短,血肿形态多为不规则,血小板水平和血浆纤维蛋白原(Fib)水平均低于无血肿扩大组;血肿扩大组出血部位位于基底节和丘脑的比例较高,而位于脑叶的比例较低。结论平均动脉压、血肿形态不规则是脑出血患者早期血肿扩大的危险因素;血小板、Fib是保护因素。积极控制血压有助于降低血肿扩大的发生率。Objective To analyze the risk factors on hematoma enlargement in patients with intracerebral hemorrhage in early stage. Methods 200 inpatients with intracerebral hemorrhage that came to our emergency during July 2009 to December 2010 were recruited in this study. The patients＇ basic information and clinical data were recorded. Finally all patients were divided into two groups according to the occurrence of hematoma enlargement based on CT examination. Univariate analyses and Logistic regression were used in order to explore the risk factors on hematoma enlargement patients with intracerebral hemorrhage in early stage. Results Among all 200 patients, 54 had early hematoma enlargement and the total incidence was 27%. The clinical features of patients with early hematoma enlargement were the high level of mean arterial pressure, short disease course, irregular shape of hematoma and the low level of platelet and plasma fibrinogen. Conclusion Mean arterial pressure, irregular shape of hematoma was risk fitetors of hema- toma enlargement ; while platelet and plasma fibrinogen were protect factors of hematoma enlargement. Actively control blood pressure is helpful to decrease the incidence of hematoma enlargement.

关 键 词：脑出血 血肿扩大 危险因素 

分 类 号：R544.1[医药卫生—心血管疾病]