核酸定量扩增技术在寄生虫及病原微生物诊断中的研究进展  

Researches progress on the nucleic acid quantitative amplification technology in the diagnosis of infectious diseases

作　　者：官威[1] 夏超明[1] 

机构地区：[1]苏州大学医学部病原生物学系,苏州215123

出　　处：《国际医学寄生虫病杂志》2012年第4期236-240,共5页International JOurnal of Medical Parasitic Diseases

基　　金：基金项目：国家重点基础研究发展计划（973项目）（2007CB513102）;苏州市科技发展计划项目（SYS201007）

摘　　要：在感染性疾病中针对寄生虫及微生物病原体的核酸检测与病原学检测具有同等的价值，而核酸定量扩增技术不仅可定性诊断，还可用于各种感染性疾病的感染度测定、疗效考核和愈后评价等。该技术已成为近年来分子诊断研究的热点之一。该文对核酸定量扩增技术在感染性疾病诊断中的研究进展作一综述。In infectious diseases nucleic acid detection aiming at pathogen of parasites and microbes has equal value with etiological detection. The technology of nucleic acid quantitative amplification not only can diagnose qualitatively, but also has important practical value for measurement of infectiosity, assessment of curative effect and evaluation of after-cure, so it has become one of research hotspots on the technology of melocular diagnosis recently. This paper summarized the studies on technology of nucleic acid quantitative amplification for diagnosis of infectious diseases.

关 键 词：感染性疾病 寄生虫 微生物 核酸定量扩增 

分 类 号：R446.1[医药卫生—诊断学]