地佐辛超前镇痛在妇科腹腔镜手术中的效果  被引量:25

Efficacy of dezocine for preemptive analgesia in gynecological laparoscopy

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作  者:李艳娜[1] 李治松[1] 张卫[1] 孙瑞广[1] 侯军凯[1] 周立君[1] 

机构地区:[1]郑州大学第一附属医院麻醉科,450052

出  处:《国际麻醉学与复苏杂志》2012年第8期517-519,共3页International Journal of Anesthesiology and Resuscitation

摘  要:目的观察地佐辛超前镇痛在妇科腹腔镜手术中的作用与效果。方法40例美国麻醉医师协会(ASA)分级I一Ⅱ级拟行腹腔镜手术的患者,采用随机数字表法随机分为两组(每组20例),地佐辛超前镇痛组(A组)、地佐辛常规镇痛组(B组)。A组于手术切皮前15min静脉注射地佐辛10mg,B组于手术结束前15min静脉注射地佐辛10mg。于术后2、4、8、12、24h随访并记录视觉模拟评分(VAS评分)、副作用发生情况。结果A组术后2、4、8、12、24h各时点VAS评分【(1.7±0.6)、(1.5±0.5)、(1.2±0.5)、(4.1±0.9)、(1.2±0.4)1低于同时点B组『(2.9±1.3)、(2.8±1.7)、(3.0±2.3)、(4.2±0.8)、(1.8±0.7)】(P〈0.05),两组患者的不良反应发生率无统计学差异(P〉0.05)。结论地佐辛超前镇痛能有效减轻妇科腹腔镜手术患者的术后疼痛,且不增加术后副作用的发生率。Objective To observe the preemptive analgesic effect of dezocine on gynecological laparoscopy. Methods Forty patients(ASA I -II )were randomly assigned into two groups. The patients in group A(n=20) received intravenous injection of dezocine 10 mg 15 rain before surgery, and those in group B (n=20) intravenous injection of dezocine 10 mg 15 min before the end of surgery. Postoperative analgesia efficacy was assessed by visual analog scales(VAS) at 2,4,8,12 and 24 h after surgery. Analgesic therapy and adverse effects were evaluated after surgery. Results VAS was lower in the group A[(1.74±0.6), ( 1.5±0.5 ), ( 1.2±0.5 ), (4.1±0.9), (1.2±0.4)] at 2,4,8, 12,24 h (P〈0.05) than that in group B [(2.9±1.3), (2.8±1.7), (3.0±2.3), (4.2±0.8), (1.8±0.7)]. There was no significant difference between the two groups in adverse effects (P〉0.05). Conclusions Dezocine for preemptive analgesia can effectively relieve postoperative pain in patients with gynecological laparoscopy, and can not increase the incidence of adverse effects.

关 键 词:地佐辛 超前镇痛 腹腔镜 

分 类 号:R614[医药卫生—麻醉学]

 

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