冠状动脉慢血流者血糖水平测定及临床研究  

Detection and clinical study on level of plasma glucose in patients with coronary slow flow

作　　者：何疆春[1] 杨晔[1] 张宁坤[1] 朱智明[1] 裘毅钢[1] 王兆君[1] 

机构地区：[1]海军总医院心脏中心,北京100048

出　　处：《中国循证心血管医学杂志》2012年第3期237-239,共3页Chinese Journal of Evidence-Based Cardiovascular Medicine

基　　金：海军总医院2009年创新基金资助(CX200908)

摘　　要：目的探讨血糖水平与冠状动脉慢血流(CSF)发病的关系。方法选择经冠状动脉造影(CAG)检查诊断为CSF者20例,CAG显示无管腔狭窄及无慢血流的正常血流速度(CNF)者24例为对照组,使用校正的TIMI血流分级(CTFC)方法评价冠状动脉血流速度,并分别测定2组的空腹血糖(FPG)、服糖后2h血糖(2h-PG)、血脂及糖化血红蛋白(HbA1c)水平。结果 CSF组与CNF组空腹血糖、餐后2h血糖、糖耐量异常者发生率比较,无统计学差异(P>0.05),但两组HbA1c水平有统计学差异(P<0.05)。结论 HbA1c水平与冠状动脉慢血流的发生有关,其水平降低有助于预防冠状动脉慢血流的发生。Objective To discuss the relationship between the level of plasma glucose and coronary slow flow （CSF）. Methods The patients （n = 20） with CSF diagnosed by coronary angiography （CAG） were selected as CSF group,and patients （n =24） with coronary normal flow （CNF） after CAG showing no angiostegnosis and slow flow as control group. The coronary flow speed was reviewed by using the method of corrected TIMI frame count. The levels of fasting plasma glucose （FPG） ,2 hours postprandial plasma glucose （2h-PG）, blood fat and glycosated hemoglobin A1 c （HbA1c） were detected in two groups. Results The comparison in the incidence of abnormal FPG,2h-PG and glu- cose tolerance between two groups showed no statistical difference （ P 〉 0.05 ） , but the level of glycosated HbA1 c had statistical difference between two groups （P 〈 0.05 ）. Conclusion The level of glycosated HbA1 c is correlated to CSF, and its decrease can prevent the occurrence of coronary slow flow.

关 键 词：冠状动脉慢血流 血糖水平 糖化血红蛋白 空腹血糖 口服葡萄糖耐量试验 

分 类 号：R541.4[医药卫生—心血管疾病]