ICU肺部感染患者痰标本的病原学分析  

Etiologic analysis of sputum from patients with pulmonary infection in ICU

作　　者：吴强[1] 汪华学[1] 郭普[2] 郑胜勇[1] 何先弟[1] 

机构地区：[1]蚌埠医学院第一附属医院ICU,安徽蚌埠233004 [2]蚌埠医学院第一附属医院检验科,安徽蚌埠233004

出　　处：《蚌埠医学院学报》2012年第8期981-984,共4页Journal of Bengbu Medical College

摘　　要：目的:了解ICU肺部感染患者主要致病菌株的分布和耐药性,为临床合理用药提供依据。方法:对2008年8月至2012年2月ICU肺部感染患者痰培养分离菌1 425株的药敏结果进行回顾性分析,药敏结果使用CLSI判断标准。结果:1 425株病原菌中革兰阴性菌占64.8%,革兰阳性球菌占19.6%,真菌占15.6%。痰培养前八位的细菌分别是鲍曼复合醋酸钙不动杆菌、金黄色葡萄球菌、铜绿假单胞菌、白色念珠菌、肺炎克雷伯菌、大肠埃希菌、表皮葡萄球菌、光滑念珠菌。药敏结果除真菌耐药率较低外,其他病原菌均有较高耐药率。结论:ICU肺部感染患者的病原菌种类多样,多重耐药菌株是监测的重点。Objective： To investigate the distribution and antibiotic resistance of pathogens that cause pulmonary infections among patients in the intensive care unit（ ICU）, and provide basis for rational selection of clinical drugs. Methods：The clinical date of 1 425 bacterial strains isolated from the sputum of patients with pulmonary infection in the ICU from Aug. 2008 to Feb. 2012 were retrospectively analyzed and validated exclusively with the CLSI standard. Results ： Of the infection pathogens, gram-negative bacteria accounted for 64. 8% , gram-positive cocci 19. 6% and fungi 15. 6%. The common clinical isolates in ICU were Acinetobacter baumannii,Staphylococcus aureus , Pseudomonas aeruginosa, Candida albicans , Klebsiella pneumoniae, Escherichia coli, Staphylococcus epidermidis and Candida glabrata, all of which showed high resistance to the antibiotics except fungi. Conclusions： The pathogen in ICU is diverse. Multidrug resistant strains are the focus of concern.

关 键 词：感染 重症监护病房 病原学 微生物敏感性试验 

分 类 号：R631[医药卫生—外科学]