小儿病毒性心肌炎的氧自由基变化及其相关因素  

The Rearch of the Changes of Oxyen Free Radicals and the Relative Factors of Viral Myocarditis in Childhood

作　　者：葛明[1] 王立琴[1] 沈德炜[1] 杨力群[1] 王伟 马沛然[3] 

机构地区：[1]济南铁路中心医院,250001 [2]山东省妇幼保健院 [3]山东省立医院

出　　处：《山东医药》2000年第10期9-10,共2页Shandong Medical Journal

摘　　要：对 61例病毒性心肌炎 ( VMC)患儿检测了 SOD、GSH— PX、MDA。发现 VMC患儿发病 1周内 SOD、GSH—PX下降 ,MDA升高 ;经大剂量维生素 C治疗后 ,SOD、GSH— PX、MDA于 4～ 6周恢复正常。 SOD、GSH—PX与 CK—MB呈负相关 ;与 EF、FS呈正相关 ;MDA与 CK—MB呈正相关 ,与GSH— PX、SOD呈负相关。MDA升高与否和心电图 ST—T改变有关 ,GSH—PX、SOD降低与否和心电图 ST—T改变无关。SOD,GSH—PX and MDA were examed in 61 cases of viral myocarditis SOD and GSH—PX were decreased in viral myocarditis and MDA was increased in viral myocarditis After treated by large dise of vitamine C,SOD,GSH—PX,MDA were returnd to normal in 4～6 weeks GSH—PX and SOD were related to CK—KB,EF and SF MDA was related to CK—KB,SOD,GSH—PX and change of ST—T

关 键 词：病毒性心肌炎 氧自由基 儿童 

分 类 号：R725.422.1[医药卫生—儿科]