萜类化合物对德国小蠊驱避活性的研究  

Repellent activity evaluation of terpenoids against German cockroaches

作　　者：韩招久[1] 王宗德[2] 姜志宽[1] 钱万红[1] 陈金珠[2] 郑卫青[3] 

机构地区：[1]南京军区军事医学研究所,江苏南京210002 [2]江西农业大学,江西南昌330045 [3]南昌市疾病预防控制中心,江西南昌330045

出　　处：《中华卫生杀虫药械》2012年第4期290-295,共6页Chinese Journal of Hygienic Insecticides and Equipments

基　　金：江苏省自然科学基金项目(编号:BK2009040);国家自然科学基金项目(编号:31060101)

摘　　要：目的筛选评估萜类化合物对德国小蠊的驱避活性。方法滤纸浸液法生物测定。结果 43个萜类化合物在剂量为340μg/cm2时对德国小蠊雄性成虫驱避活性的初步测试结果显示,羟基香茅醛、薄荷醇、羟基香茅醛丙酸酯、龙脑烯醛缩-1,3-丙二醇等4个化合物表现出了较高的驱避活性。对这4个化合物采用几何浓度梯度进一步测试,并与目前广泛应用的昆虫驱避剂避蚊胺(DEET)进行比较。羟基香茅醛、薄荷醇、羟基香茅醛丙酸酯、龙脑烯醛缩-1,3-丙二醇的驱避中量(RD50)分别为154.7、56.2、165.9和151.3μg/cm2,均低于DEET的RD50(194.5μg/cm2)。结论本项研究结果说明,羟基香茅醛、薄荷醇、羟基香茅醛丙酸酯、龙脑烯醛缩-1,3-丙二醇具有作为蟑螂驱避剂的应用前景。Objective To screen and evaluate the repellent activity of terpenoids compounds isolated or synthesized from turpentine against adult male German cockroaches（Blattella germanica）. Methods Bioassay with dipped filter pa- pers. Results Among those 43 terpenoids compounds, four compounds, namely hydroxycitronellal, menthol, hydroxy- citronellal propionate and campholenie aldehyde propylene glycol 1,3 - acetal displayed the most powerful activity in the preliminary screening test using dipped filter paper at the dose of 340 μg/cm2. Further test with geometric series doses for the RD50s （dose of 50% repellency） reveal that the RD50s were 154.7, 56.2, 165.9 and 151.3 μg/cm2 for hydroxycitronellal, menthol, hydroxycitronellal propionate and campholenic aldehyde propylene glycol 1,3 - acetal re- spectively, less than diethyltoluamide （DEET） with the RD50 of 194.5 μg/cm2. Conclusion It is supposed that these four terpenoids, hydroxycitronellal, menthol, hydroxycitronellal propionate and eampholenic aldehyde propylene glycol 1,3 - acetal would be potential and promising cockroach repellents.

关 键 词：萜类化合物 德国小蠊 驱避活性 

分 类 号：S482.38[农业科学—农药学] R184.3[农业科学—植物保护]