沙美特罗替卡松吸入治疗儿童支气管哮喘的临床疗效观察  

The Clinical Observation of Salmetero Xinafoate and Fluticasone Propionate Aerosol Treated on Asthma of Children

作　　者：黄葆莹[1] 何丽仪[1] 苏健[1] 

机构地区：[1]广东省佛山市第一人民医院儿科,528000

出　　处：《大众健康（理论版）》2012年第6期95-96,共2页

摘　　要：目的：探讨沙美特罗替卡松吸入治疗儿童支气管哮喘的临床疗效。方法：选择我院2009年5月至2011年5月诊治的儿童支气管哮喘患者80例，随机将上述患者分为观察组和对照组，每组40例，对照组给予布地奈德气雾剂治疗，观察组给予沙美特罗替卡松吸入治疗，两组患者均治疗10天，在治疗期间观察两组患者哮喘临床症状的缓解情况，同时观察治疗前后患者肺功能（FEV1和PEF预计值％）的变化。结果：观察组总有效率为97．5％，对照组总有效率为82．5％，两组有效率比较，差异具有统计学意义，P〈0．05：观察组和对照组FEV1和PEF值都有明显改善，与治疗前相比差异均具有统计学意义，P〈0．05。而治疗后观察组FEV1和PEF值改善更显著，与对照组相比，差异具有统计学意义，P〈0．05；观察组不良反应发生率分别为2．5％，对照组为5．0％，两组不良反应比较差异无统计学意义，P〉0．05。结论：沙美特罗替卡松吸入治疗能够显著控制儿童支气管哮喘急性发作症状，改善患者临床症状显著。Objective;To observe the effect of salmetero xinafoate and fluticasone propionate aerosol on children＇s asthma. Method .. 80 children with asthma were divided into two groups; each group is 40 patients.The observation group is treated by salmetero xinafoate and fluticasone propionate aerosol, and the control group is treated by budesonide aerosol. To observe the solution of wheezle, FEV1 and PEF before and past the treatment. Result.The effective rate of the observation group was 97.5%, the total effective rate of 82.5% in the control group, two groups have an efficient comparison, a statistically significant difference, P 〈 0.05. The rate of FEV1 and PEF was improved siganiffically. The variance was statistically significant with the control group, P〈0.05.The happeness of adverse reactions in observation group was 2.5%, and 5% in the control group. There was no statistically difference, P〉0.05. Conclusions.. Salmetero xinafoate and fluticasone propionate aerosol can treat the clinical syndroms of children＇s asthma in acute exacerbation.

关 键 词：沙美特罗替卡松 布地奈德 吸入治疗 儿童支气管哮喘 

分 类 号：R72[医药卫生—儿科]