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作 者:周林海[1] 梁碧荣 张怀勤[1] 黄伟剑[1] 林捷[1] 计光[1] 胡建琼[1] 吴高俊[1] 虞晓武[3]
机构地区:[1]温州医学院附属第一医院心内科,325000 [2]温州市中西医结合医院影像科 [3]温州医学院附属第三医院心内科
出 处:《中国医师进修杂志》2012年第22期4-7,共4页Chinese Journal of Postgraduates of Medicine
摘 要:目的探讨心率震荡(HRT)对糖尿病患者急性心肌梗死后的预测价值。方法选择92例急性心肌梗死合并糖尿病患者(糖尿病组)和120例急性心肌梗死未合并糖尿病患者(非糖尿病组)为研究对象,HRT的两个参数震荡初始(TO)≥0和震荡斜率(TS)≤2.5ms/R。R认为是阳性,比较两组HRT阴性和阳性患者临床资料的差异,并对急性心肌梗死后的相关危险因素进行分析。结果糖尿病组HRT阳性和阴性患者在年龄、左室射血分数(LVEF)水平、肾功能不全、LVEF〈40%、窦性心动周期(R-R间期)的标准差(SDNN)、心率变异性(HRV)阳性和HRT参数(TO、TS)方面比较差异有统计学意义(P〈0.05)。非糖尿病组HRT阳性和阴性患者在年龄、LVEF水平、SDNN和HRT参数(TO、TS)方面比较差异有统计学意义(P〈0.05)。在多因素Cox回归分析中,糖尿病组肾功能不全(OR值为4.8,95%CI:1.8~10.7,P=0.008)和HRT阳性(OR值为3.7,95%CI:1.5~8.6,P=0.070)差异有统计学意义。非糖尿病组HRT阳性差异有统计学意义(OR值为23.0,95%CI:5.2~86.0,P〈0.01)。结论动态心电图参数HRT能够预测糖尿病患者和非糖尿病患者急性心肌梗死后的危险性。Objective To investigate the predictive value of heart rate turbulence(HRT) in patients with diabetes mellitus (DM) after acute myocardial infarction (AMI). Methods Ninety-two AMI patients combined with DM (DM group) and 120 AMI patients without DM (non-DM group) were selected. Turbulence onset (TO) and turbulence slope (TS) were two indexes of HRT. HRT was considered positive when TO was I〉0 and TS was ~〈2.5 ms/R-R. The differences in clinical data between HRT-positive and HRT-negative patients were compared. And the related risk factors after AMI were analyzed. Results Age, left ventricular ejection fraction (LVEF) level, renal insufficiency, LVEF〈40%, standard deviation of sinus cardiac cycle (R-R interval)(SDNN), heart rate variability (HRV) positive and HRT indexes (TO,TS) between HRT-positive and HRT-negative patients in DM group had significant differences (P 〈 0.05). Age, LVEF level, SDNN and HRT indexes (TO, TS) between HRT-positive and HRT-negative patients in non-DM group had significant differences (P 〈 0.05). Multivariate Cox regression analysis showed that renal insufficiency (OR = 4.8,95% CI: 1.8 -10.7,P = 0.008) and HRT positive (OR = 3.7,95% CI: 1.5 - 8.6, P = 0.070) in DM group had statistical significance. And HRT positive in non-DM group had statistical significance (OR = 23.0,95% CI:5.2 ~ 86.0,P 〈 0.01 ). Conclusions HRT,an index of dynamic electrocardiogram,can predict the risk in patients with DM or without DM after AMI.
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