老年糖尿病合并脑梗死患者C反应蛋白检测及临床意义  

Detection and significance of C-reactive protein in elderly patients with diabetes mellitus and cerebral infarction

作　　者：刘玮[1] 赵瑞敏[1] 陈大伟[1] 陈晋文[1] 杜文津[1] 李华军[1] 靳雁斌[1] 

机构地区：[1]空军总医院神经内科,北京100142

出　　处：《中国医师进修杂志》2012年第22期11-13,共3页Chinese Journal of Postgraduates of Medicine

摘　　要：目的探讨老年糖尿病合并脑梗死患者血清C反应蛋白（CRP）的检测及其临床意义。方法选取2008年10月至2011年1月收治的糖尿病合并脑梗死患者72例（糖尿病脑梗死组），非糖尿病合并脑梗死患者66例（tP糖尿病脑梗死组），健康体检者60例（对照组）。检测其血清CRP水平。结果糖尿病脑梗死组CRP水平为（3．81±2．23）mg／L，非糖尿病脑梗死组CRP水平为（2．48±2．24）mg／L，对照组CRP水平为（0．68±0．16）mg／L，糖尿病脑梗死组、非糖尿病脑梗死组与对照组比较，CRP水平显著升高，差异有统计学意义（P〈0．05）；糖尿病脑梗死组与非糖尿病脑梗死组比较，CRP水平显著升高，差异有统计学意义（P〈0．05）。糖尿病脑梗死组CRP异常率为70．8％（51／72），非糖尿病脑梗死组CRP异常率为43．9％（29／66），两组比较差异有统计学意义（P〈0．05）。结论CRP对糖尿病性脑梗死的发生发展有重要的预测价值。Objective To evaluate the significance of the detection of serum C-reactive protein （CRP） in elderly patients with diabetes mellitus and cerebral infarction. Methods Seventy-two patients with diabetes mellitus and cerebral infarction （diabetic cerebral infarction group）,66 patients with cerebral infarction and without diabetes mellitus （non-diabetic cerebral infarction group） and 60 healthy persons （control group） from October 2008 to January 2011 were selected. The level of serum CRP was detected. Results The level of CRP was （ 3.81 ~ 2.23 ） mg/L in diabetic cerebral infarction group, （2.48 ＋ 2.24） mg/L in non-diabetic cerebral infarction group and （0.68 ＋ 0.16） mg/L in control group. The levels of CRP in diabetic cerebral infarction group and non-diabetic cerebral infarction group were significantly higher than that in control group （P 〈 0.05 ）. The level of CRP in diabetic cerebral infarction group was obviously higher than that in non-diabetic cerebral infarction group （P 〈 0.05）. CRP abnormal rate was 70.8% （51/72） in diabetic cerebral infarction group and 43.9%（29/66） in non-diabetic cerebral infarction group,which had statistical significance （P 〈 0.05 ）. Conclusion CRP has important predictive value to the occurrence and development of diabetic cerebral infarction.

关 键 词：老年人 糖尿病 脑梗塞 C反应蛋白质 

分 类 号：R587.1[医药卫生—内分泌] R743.3[医药卫生—内科学]