2009-2011年浙江省台州市手足口病重症病例流行特征及危险因素分析  

Epidemiological characteristics and risk factors of severe cases of hand,foot and mouth disease in Taizhou,Zhejiang,2009-2011

作　　者：陈潇潇[1] 林海江[1] 常玥[1] 

机构地区：[1]台州市疾病预防控制中心,浙江台州318000

出　　处：《疾病监测》2012年第7期545-547,561,共4页Disease Surveillance

摘　　要：目的了解浙江省台州市手足口病重症病例流行病学特征和危险因素,为进一步制定防控措施提供参考依据。方法应用描述流行病学方法对台州市2009-2011年手足口病重症病例的流行特征进行分析,并运用logistic回归分析方法研究手足口病重症病例的危险因素。结果 97.10%的重症病例<5岁,男性多于女性,散居儿童重症病例构成比高于其他人群;全市9个县(市、区)均有重症病例报告;5-6月为重症发病高峰。重症病例以EV71型为主。多因素logistic回归分析结果显示流动人口、精神状态差、呕吐、EV71阳性是手足口病重症发生的危险因素。结论应在外来人口聚集地等重点地区,针对小年龄组儿童家长,有针对性地开展宣传教育工作,并早期监测手足口病重症危险因素,及时对症治疗,以降低手足口病病死率。Objective To understand the epidemiological characteristics and risk factors of severe cases of hand, foot and mouth disease （HFMD） in Taizhou, and provide scientific evidence for the prevention and control of HFMD. Methods Descriptive epidemiological analysis was conducted on the incidence data of severe cases of HFMD in Taizhou from 2009 to 2011 and logistic regression analysis was done to identify the related risk factors. Results Over 97.10% of severe HFMD cases were children aged ≤5 years and more boys were affected than girls. The severe cases in children outside child care settings accounted for higher proportion. The severe cases were reported in all districts or counties of Taizhou and the incidence peak of severe cases was during May-June. The severe cases were mainly caused by EV71 infection. Multivariate logistic regression analysis indicated that the risk factors included being non-local resident; fatigue, vomiting and EV71 infection. Conclusion It is necessary to conduct health education in floating population to increase their awareness of HFMD to reduce the incidence of HFMD, and strengthen the monitoring of risk factors of severe HFMD and give timely treatment to reduce the case-fatality.

关 键 词：手足口病 流行特征 重症病例 危险因素 

分 类 号：R725.1[医药卫生—儿科] R181.3[医药卫生—临床医学]