对样本接力跟踪检测质量控制法的差值校正  

Calibration of Difference Value for the Method of Quality Control to the Sample Being Tailed Inspection

作　　者：魏志武[1] 

机构地区：[1]白银市第二人民医院检验科,甘肃白银730900

出　　处：《现代检验医学杂志》2012年第3期83-85,共3页Journal of Modern Laboratory Medicine

摘　　要：目的在“样本接力跟踪检测质量控制法的初步应用”一文方法的基础上，针对在实际应用中可能出现的WBC计数“集中值质控样本（Z样本）”“集中度”不可控的情况，创建“差值校正”方案，以使该法能在更自然宽限的范围择选“Z样本”，使“累积差值（Si）”更准确灵敏地跟踪于“0”偏差。方法对“接力法”原理及检测原理、偏差本质作进一步延伸分析解读，创建差值校正公式，即：校正差值（当批次Z样本）=当批次Z样本差值＋（首批次Z样本首测值一当批次Z样本首测值）×当批次Z样本偏差％；以校正差值采计算Si。结果接力法系列Z样本原始差值经校正后，均相当于在首批次Z样本含量值水平下产生的“差值”，即时消除了Z样本含量值“集中度”低时对Si可信度及灵敏度的影响。结论差值校正公式具有合理性，可解决因系列Z样本值的不统一性而引入的“差值干扰”；差值校正后可提高Z样本同时开展多项目质控的适用性。Objective On method from the basis of ＂initial application of quality control method for the sample tailed inspection＂ aimed at tile incontrollable situation of ＂collection degree＂ for ＂collection value quality controlled sample （Z sample）＂ during the period of counting WBC. which maybe appear in the actual application,set up a plan ＂calibration of difference value＂ to make the method could had a nature wider selection scope in＂Z sample＂ for the purpose of ＂cumulation of difference value（ Si）＂could tail more nicety and sensitive to the＂0＂difference. Methods By more extension analysis to the method theory, test principle and deviation reason, the calibration formula could be set up. Namely, difference value of calibration （Z sample of actual bench ）= actual bench difference value of Z sample＋ （tile first value of tile first Z sample-first value of actual bench Z sample） × difference value of actual bench Z sample% Si was calculated by the help of difference value of calibration. Results After calibration, all the original difference value of Z sample in series of trailed method correspond to tile ＂difference value＂ at the level of content value for the first sample,timely eliminating the influence of reliability and sensitive degree to Si caused by low content of ＂＇collection degree＂. Conclusion Calibration formula of difference value is reasonable, which may solve the ＂interference of difference value＂ caused by the difference of the series Z sample value; after calibration of difference value, the applicability of Z sample being used for quality control to more items can be improved.

关 键 词：样本接力跟踪检测质量控制法 差值校正 提高适用性 

分 类 号：R446[医药卫生—诊断学]