睡眠紊乱与糖尿病关系的研究进展  

Relationship between sleep disorder and diabetes melUtus

作　　者：冯红[1] 徐勇[1] 

机构地区：[1]泸州医学院附属医院内分泌科,646000

出　　处：《国际内分泌代谢杂志》2012年第4期231-233,共3页International Journal of Endocrinology and Metabolism

摘　　要：长期睡眠紊乱可改变机体神经一内分泌功能，使血中升血糖激素、细胞因子水平升高，引起胰岛素抵抗、肥胖等病理生理改变，导致糖尿病的患病风险明显升高。同时，糖尿病引起的中枢神经系统与神经递质异常，急、慢性并发症的发生、发展，及其所带来的心理负担等，都极易影响患者的睡眠模式和质量，引起睡眠紊乱。糖尿病与睡眠紊乱关系密切，改善睡眠质量可明显提高胰岛素敏感性，改善血糖控制，起到辅助治疗糖尿病的作用。Long-term sleep disorder may cause significantly change of neural incretion function,in- crease the level of plasma hormones that raise glucose level and adipokines, which results in pathophysiologi-ca1 changes including insulin resistance and obesity, and increase the risk of diabetes mellitus. At the same time, the disorders caused by diabetes mellitus, such as the abnormity of neural system and neurotransmitter, the development of acute and chronic complications and the psychological burden, could affect the patients＇ sleeping mode and quality and lead to sleeping disorder. Diabetes mellitus and sleep disorder have close rela-tionship. Improving sleep quality can obviously improve insulin sensitivity and glycemic control, which plays an indeed role for the auxiliary therapy for diabetes.

关 键 词：睡眠紊乱 糖尿病 肥胖 胰岛素抵抗 

分 类 号：R587.1[医药卫生—内分泌]