男男性行为者艾滋病病毒及梅毒感染状况调查  

HIV and syphilis infections among men who have sex with men

作　　者：周建波[1] 郝超[1] 还锡萍[2] 王金塔[1] 甄森[1] 郭燕丽[1] 史太平[1] 尹跃平 

机构地区：[1]常州市疾病预防控制中心性病艾滋病控制所,江苏213022 [2]江苏省疾病预防控制中心性病艾滋病控制所 [3]中国医学科学院皮肤病研究所参比实验室

出　　处：《中国公共卫生》2012年第8期1031-1035,共5页Chinese Journal of Public Health

基　　金："艾滋病和病毒性肝炎等重大传染病防治"国家科技重大专项(2008ZX10001-005);常州市卫生局重大项目(ZD200905)

摘　　要：目的了解江苏省常州市男男性行为者(MSM)的人口学和行为学特征、艾滋病病毒(HIV)和梅毒感染情况及其影响因素。方法通过问卷调查收集人口学、相关健康服务及行为学等信息,并采集血液和尿样标本分别进行HIV和梅毒抗体、及淋球菌和生殖道沙眼衣原体检测。结果共有效调查593名MSM,HIV和梅毒感染率分别为13.7%(81/593)和31.2%(185/593),同时感染HIV和梅毒者占7.1%(42/593);5.7%(34/592)曾经发生过性虐待;在近6个月,63.9%(379/592)与男性发生过肛交行为,76.0%(288/379)在最近1次肛交中使用安全套,47.2%(280/592)与女性发生过性行为,53.2%(149/280)在最近1次与女性发生性行为时使用安全套;非条件多元logistic回归分析结果显示,感染HIV的危险因素为年龄偏大、学生、有过性虐待、梅毒抗体阳性;梅毒感染的危险因素为HIV抗体阳性、有过性虐待出血。结论常州市MSM人群普遍存在高危性行为,其HIV和梅毒感染率已达较高水平;应采取HIV和性传播感染(STI)筛查及性病规范诊疗等综合防治措施。Objective To explore demographic characteristics,human immunodeficiency virus（HIV） high-risk behavior,and the prevalence and influencing factors of HIV and syphilis infections among men who have sex with men（MSM）in Changzhou city.Methods Questionnaire interview was conducted to collect information on demographic characteristics,behaviors of sex and drug use,HIV and sexually transmitted infections（STIs）related health services.Blood and urine samples were tested for HIV/syphilis antibodies and Neisseria gonorrhoeae（NG） and Chlamydia trachomatis（CT） infections.Results Of 593 participants,13.7%（81） were HIV-positive,31.2%（185） were sero-positive for syphilis infection,and 7.1%（42） were both HIV-positive and sero-positive for syphilis infection.There were 5.7%（34/592） of MSM having sexual abuse.In the latest 6 months,63.9%（379/592） of the MSM had anal sex with men,of which 24%（91/379） did not use condom in the recent anal sex.There were 47.2%（280/592） of the MSM having sex with women,of which 46.8%（131/280） did not use condom in the recent vaginal sex with women.Factors associated with HIV infection included age（χ2=14.83,P=0.005）,occupation（χ2=11.06,P=0.047）,sex abuse（odds ratio=2.97,95% confidence interval1.26-7.01）,syphilis infection（OR=3.17,95%CI：1.88-5.35）.The risk of HIV infection for student MSM was three times of that in workers/migrant workers（OR=3.01,95%CI：1.04-8.72）.Factors associated with HIV infection included positive for HIV infection（OR=10.60,95%CI：1.09-103.55）and bleeding in sex abuse（OR=11.95,95%CI：1.27-112.68）.Conclusion The HIV-high risk sex behavior was prevalent among MSM population in Changzhou city and the prevalence rates of HIV and syphilis infection were high.Screening of HIV and STIs and normative treatment to the diseases are essential in the high risk population.

关 键 词：男男性行为者 艾滋病病毒(HIV) 梅毒 性传播感染(STI) 

分 类 号：R512.9[医药卫生—内科学] R759[医药卫生—临床医学]