神经中轴钙化性假瘤的影像特征  

Imaging features of calcifying pseudoneoplasms of the neuraxis

作　　者：李代兵[1] 楼俭茹[2] 王海屹[1] 王湛博[3] 马林[1] 娄昕[1] 田志诚[4] 

机构地区：[1]解放军总医院放射科,北京100853 [2]新疆医科大学附属中医医院影像中心 [3]解放军总医院病理科,北京100853 [4]四川省遂宁市第一人民医院放射科

出　　处：《中华放射学杂志》2012年第8期708-711,共4页Chinese Journal of Radiology

摘　　要：目的探讨神经中轴钙化性假瘤（CAPNON）的影像特征，提高对该病的诊断水平。方法5例经病理证实的CAPNON患者术前均进行MR检查，其中4例同时行CT检查，2例行DSA检查，1例行SPECT骨扫描。对所有患者的影像资料进行回顾性分析。结果5例患者年龄为25～60岁，平均（50±11）岁。男4例，女1例。病灶直径1．5～5．0cm。病灶3例位于颅底，1例位于椎管，1例位于枕颈交界区。cT平扫均呈钙化影。MR平扫，T1WI为等低信号，T2WI中4例为等低信号、1例为高低混杂信号；MR增强扫描，3例周边强化、1例无强化、1例均匀强化。病理上可见钙化组织、纤维上皮组织及黏液样基质。5例周围均无水肿。结论CAPNON好发于成人男性，神经中轴部位常见，CT以钙化为主，MR以等低信号及周边强化为主，有助于诊断。Objective To identify the imaging characteristics of calcifying pseudoneoplasms of the neuraxis （CAPNON） and do literature review. Methods Five patients of pathologically-proved CAPNON underwent preoperative MR examination, among which 4 underwent CT scan, 2 underwent DSA examination and 1 underwent SPECT. All imaging data were retrospectively analyzed with the emphasis on imaging characteristics. Results Five patients of CAPNON with the diameter of 1.5 to 5.0 em were found in five patients （ Male 4 ; Female 1 ; age 25 to 60 years old）. Three lesions were located in the skull base, one was located in the cervical spine and one in the foramen magnum and upper cervical segment. All patients underwent MRI examination and 4 of them also took CT scanning. On plain CT, all lesions showed obvious calcification. On T1WI all masses showed hypointensity, and on T2WI 4 of the lesions showed iso- or hypointensity and 1 heterogeneous signal intensity. On contrast-enhanced MR images, peripheral enhancement was demonstrated in 3 lesions, homogeneous enhancement was found in case and one lesion showed no enhancement. The pathologic analysis indicated that inside the lesions were abundant calcification, fibroepithelial tissue and mucoid matrix and no edema was detected around the lesions. Conclusions CAPNON displayed the predilection to male adults and the neuraxis was the predilection site. Calcification on CT images, hypointensity on MR images and peripheral enhancement will be helpful for the diagnosis of CAPNON, but the final confirmation still needs the pathologic results.

关 键 词：肉芽肿 磁共振成像 体层摄影术 X线计算机 

分 类 号：R816.1[医药卫生—放射医学]