三维能量超声联合彩色多普勒监测妊娠高血压综合征患者胎盘血流的临床研究  

Clinical Research of Three-dimensional Color Power Ultrasound Combined with Color Doppler Imaging for the Assessment of Placental Perfusion in Patients with Pregnancy-induced Hypertension

作　　者：雷蓓[1] 刘雪玲[1] 连溯[1] 成平[1] 骆峰[1] 伍业冬[1] 李坚[1] 

机构地区：[1]广西中医药大学第一附属医院超声科,南宁市530022

出　　处：《广西医学》2012年第9期1130-1132,共3页Guangxi Medical Journal

基　　金：广西自然科学基金(桂科自0728179)

摘　　要：目的探讨三维超声彩色能量成像(3D-CPA)联合彩色多普勒超声(CDFI)技术定量评价妊娠高血压综合征(PIH)患者胎盘血流情况的价值。方法 90例PIH孕妇中,轻度子痫前期53例(P-L组),重度子痫前期37例(P-H组),同期选取100例正常孕妇为正常对照组(N组)。对所有孕妇胎盘床血管进行三维重建,采用VOCAL软件测量血管化指数(VI),血流指数(FI),血管化血流指数(VFI)。采用CDFI测量脐动脉收缩期/舒张期血流速度峰值(S/D),并与正常对照组比较。结果 P-L组、P-H组与N组S/D值比较,差异有统计学意义(P<0.01),P-H组高于P-L组、N组(P<0.01)。P-L组、P-H组VI、FI、VFI与N组比较,差异有统计学意义(P均<0.01),均为P-H组<P-L组<N组。结论 PIH患者S/D值升高,VI、FI、VFI值降低,且以重度子痫前期为明显。3D-CPA技术可更早更精确地提示PIH患者的胎盘血流灌注情况。Objective To investigate the clinical value of three-dimensional color power angiography（3D-CPA） and color Doppler flow imaging （ CDFI ） in the quantitate assessment of placental perfusion in pregnancy-induced hypertension（PIH） patients. Methods Ninty pregnant women with PIH were divided into the mild pre-eclampsia group（ n = 53, Group P-L） and severe pre-eclampsia group （n = 37, Group P-H）, 100 healthy pregnant women as the controls（ Group N）. Three-dimensional reconstruction of placental vascular was performed,and placental vascularization index（V I）,flow index（F[）,and vascularization-flow index（VFI） were measured with VOCAL software. CDFI was used to measure the umbilical blood flow systolic to diastolic （S/D）. The data in PIH patients were compared with the controls. Results There was significant difference in S/D between Group P-L and Group N, as well as between Group P-H and Group N （ P 〈 0.01 ）, and S/D was significantly higher in Group P-H than in Group P-L, and Group N （ P 〈0.01 ）. VI,FI and VFI showed significant difference between Group P-L and Group N,as well as between Group P-H and Group N（all P 〈0.01） ,which were lowest in Group P-H and highest in Group N. Condusion S/D increased and VI, FI,VFI decreased in PIH patients,especially in the patients with severe pre-eclampsia. 3D-CPA could suggest placental perfusion in PIH patients earlier and more accurately.

关 键 词：妊娠期高血压疾病 胎盘 三维能量超声 彩色多普勒 

分 类 号：R714.246[医药卫生—妇产科学]