两种聚合物试剂应用于单锅合成反应中的研究──取代苯氧基苯乙酮的合成  

THE STUDY ON USING TWO DIFFERENT REACTIVE POLYMERIC REAGENTS IN ONE-POT ORGANIC SYNTHETIC REACTION-SYNTHESIS OF SUBSTITUTED PHENOXY ACETOPHENONE

作　　者：陈祖兴[1] 柳利[1] 

机构地区：[1]湖北大学化学与材料科学学院,武汉430062

出　　处：《离子交换与吸附》2000年第3期275-279,共5页Ion Exchange and Adsorption

摘　　要：探讨了聚合物支载的过溴离子及取代苯氧基离子于单锅中，以苯乙酮为底物，合成取代苯氧基苯乙酮的方法，并与分步合成法相比较．实验表明，此合成方法具有操作简便，反应条件温和，无须分离中间体，且产率较高等优点，并探索了温度、溶剂、反应时间及树脂的用量等对一锅法产率的影响．Substituted phenoxy acetophenone was synthesized by an one-pot reaction of acetophenone with polymer-supported bromine and substituted phenoxide. Comparing with the synthesis individually followed by isolation, it had mild reaction conditions and higher yields,avoiding the need to isolate the intermediates. And we try detailed to find out the facts which influence the yields such as reaction temperature, solvents, reaction time and the quantity of resins.

关 键 词：聚合物试剂 一锅法 取代苯氧基苯乙酮 合成 

分 类 号：O625.42[理学—有机化学]