女性沙眼衣原体和解脲支原体感染与妊娠不良关系探讨  

Analysis of the relationship between Chlamydia trachomatis/Ureaplasma urealyticum(CT&UU) infection and pregnancy defects

作　　者：蔡湘芬[1] 方芸萍[1] 刘静华[1] 李泽荣[2] 

机构地区：[1]潮州市妇幼保健院,广东潮州521000 [2]广州市疾病预防控制中心,广东广州510440

出　　处：《热带医学杂志》2012年第8期1002-1003,1047,共3页Journal of Tropical Medicine

摘　　要：目的探讨沙眼衣原体（cT）和解脲支原体（UU）感染与妊娠结局的关系，以指导感染监测、孕期监测及防治。方法以胚胎停育和自然流产者作为妊娠不良观察组（n=87），选取〉28周分娩者作为对照组（n=342）进行cT和UU的检出率比较。结果观察组病例的GT和UU检出率分别为41．38％和34．48％。明显高于对照组的10．82％和18．13％，差异有统计学意义（P=0．0001）。胚胎停育者的UU检出率（27．78％）略低于自然流产者（45．45％）（x2=2．8329，P=0．0923）。妊娠不良结局的复发一致性检验kappa=0．8989。结论CT和UU感染或为妊娠不良的重要原因，并存在个体反应的差异性和致病机制稳定性。Objective To investigate the relationship between Chlamydia trachomatis / Ureaplasma urealyticum （ CT＆UU ） infection and pregnancy outcomes, thus to promote the relevant surveillance and medical care. Methods Participants is divided into pregnancy defects group （including fetal cease and spontaneous abortion） and the control. CT/UU Lab testing was done and the the difference of the detection rates were analyzed. Results Of the total 87 pregnancy defects cases, the positive rate of CT（41.38%） and UU（34.48%） are both higher than those of the control（x2=45.8726, P= 0.0001 ; x2= 11.0113, P=0.0001 ）. The positive rate of UU among the fetal cease cases （27.78%） is fairly lower than that of the spontaneous abortion （45.45%） （x2=2.8329,P=0.0923）. The pregnancy defects outcomes of newly onset is accordant with the history （kappa=0.8989）. Conclusion Chlamydia trachomatis/Ureaplasma urealyticum （CT＆UU） infection may cause pregnancy defects, showing individual variation and different mechanisms.

关 键 词：沙眼衣原体 解脲支原体 妊娠不良 自然流产 胚胎停育 

分 类 号：R714.2[医药卫生—妇产科学]