聚维酮碘消毒减少导尿管相关性尿路感染的临床观察  

Efficacy of povidone-iodine intervention to reduce catheter-associated urinary tract infections

作　　者：曾娟琴[1] 韩斌德[2] 胡欣春[2] 邬海[2] 边泽源[3] 

机构地区：[1]江西省胸科医院手术室,江西南昌330006 [2]江西省胸科医院胸外科,江西南昌330006 [3]江西省胸科医院检验科,江西南昌330006

出　　处：《中华医院感染学杂志》2012年第16期3589-3591,共3页Chinese Journal of Nosocomiology

基　　金：江西省卫生厅科技计划项目(20073158)

摘　　要：目的探讨导尿时尿道注入聚维酮碘消毒,对减少导尿管相关性尿路感染的作用。方法 196例术前需留置导尿的患者随机分为对照组及试验组各98例,对照组行常规尿道外口及其周围器官皮肤消毒,按常规无菌操作技术行导尿,试验组在常规消毒的基础上,加用注射器从尿道外口注入0.5%聚维酮碘行全尿道消毒,余操作同对照组;两组均定期留取尿液标本做细菌培养及尿常规检查。结果第5、7、10天试验组尿路感染发生率分别为2.27%、7.69%及22.73%,明显低于对照组的10.11%、25.49及66.67%,差异有统计学意义(P<0.05);而留置导尿管第2、13、>16天的尿路感染发生率两组差异无统计学意义。结论尿道注入聚维酮碘消毒对减少早期导尿管相关性尿路感染是一种简便有效的方法。OBJECTIVE To explore the efficacy of povidone-iodine as is injected to the urinary tract and its effect on reducing the catheter-associated urinary tract infections. METHODS A total of 196 patients who intended to the indwelling urethral catheter before the surgery were randomly divided into the control group and the study group with 98 cases in each, the urinary catheters were inserted in the control group who received the disinfection of ex- ternal orifice of urethra and its surrounding skin according to routine aseptic technique protocol, while the test group received the extra-disinfection of the whole urethral using povidone-iodine besides routine aseptic technique protocol before the urinary catheters were inserted, and then the urinary specimens were taken out regularly from two groups respectively for urine routine examination and microbial culture. RESULTS The incidence rates of UTI were 2.27%, 7.69% and 22.73%, respectively in the study group on the 5th, 7th and 10th day, which were significantly lower than 10. 11%, 25.49% and 66.67% respectively of the control group, the differences were statistically significant （P〈0.05）3 the difference in the incidence rate of urinary tract infections on the 2nd, 13th and 16th day was not statistically significant. CONCLUSION The application of the povidone-iodine for disinfection is a simple and valid method to prevent the catheter-associated urinary tract infections in the early stage.

关 键 词：聚维酮碘 导尿管相关性尿路感染 细菌培养 

分 类 号：R187[医药卫生—流行病学]