胼胝体变性与梗死的MRI表现探讨  

Study Marchiafava-Bignami Disease (MBD) and Corpus Callosum Infarction from MRI

作　　者：苏国华[1] 陈长波[1] 马力[1] 王涛[1] 于周[1] 

机构地区：[1]凉山州第一人民医院,四川西昌615000

出　　处：《中外医学研究》2012年第22期3-5,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的：探讨胼胝体变性与梗死的MRI 及临床表现.方法：回顾性分析12 例胼胝体变性及6 例胼胝体梗死患者的MRI 表现及临床资料.12 例胼胝体变性患者均为男性,年龄53～60 岁,其中9 例有明确的酗酒史,有头昏、精神症状、智力下降、肢体无力、语言障碍、共济失调等不同症状,1 例伴有癫痫.6 例胼胝体梗死病例男女各3 例,年龄45～50 岁,以肢体活动障碍、语言障碍及头昏为主要症状.所有病例均行常规MRI 扫描,2 例变性患者和1 例梗死患者治疗后复查.结果：胼胝体变性病均累及胼胝体全程,病变呈双侧对称性分布,表现为T1WI 低信号,T2WI 高信号,FLAIR高信号,DWI 高或稍高信号;慢性患者胼胝体萎缩,FLAIR 胼胝体中心呈稍低信号,矢状位呈夹心蛋糕状;胼胝体梗死病例均表现为T1WI 低信号,T2WI 高信号,FLAIR 高信号,DWI 高信号,病灶分布在胼胝体体部前4/5 大部分区域,单侧分布并累及同侧大脑实质,或胼胝体单侧局限性病灶.2 例胼胝体变性患者治疗后复查,病变大小、形态及信号未见明显改变;1 例胼胝体梗死患者治疗后复查,病灶稍有缩小.结论：MRI 可直观显示胼胝体变性及梗死病灶的部位及范围,是胼胝体变性及梗死诊断及鉴别诊断最客观的参考指标,为临床进一步治疗提供重要的影像学依据.Objective ：To study MRI findings of Marchiafava-Bignami disease（MBD） and infarction. Methods ： Rretrospectively analyzed 12 cases of MBD and 6 cases of corpus callosum infarction in patients with MRI and clinical data. 12 cases of MBD patients were male, 53-60 years old, of which nine patients had definite history of alcohol abuse, dizziness, psychiatric symptoms, mental decline, limb weakness, language barriers, ataxia symptoms, 1 case with epilepsy. 6 cases of corpus callosum infarction cases were men and women by half, 45-50 years old, mainly had physical activity barriers, language barriers, and dizziness. All patients were underwent conventional MR｜ scans, in which 2 cases of MBD patients and 1 cases of corpus callosum infarction were rechecked after treatment. Results ： 12 cases MBD had the performance of low signal on T1WI, high signal on T2Wi and FLAIR, high or slightly higher signal on DWI, d cases of chronic patients with corpus callosum body atrophy, slightly low signal on FLAIR in corpus callosum center and the sagittal plane showed a layer cake-like ; all cases of MBD involving the entire corpus callosum, the lesions were bilateral symmetrical, 3 cases lesions involving the bilateral centrum semiovale white matter, was also symmetrical. 6 cases of corpus callosum body infarction cases showed low signal on T1WI, high-signal on T2WI, FLAIR and DWI. 4 cases distributed in the body of the body parts of the corpus callosum before 4/5 majority of regional, unilateral distribution and involving the ipsilateral brain in real terms, 2 cases of unilateral localized foci of the corpus callosum. 2 cases of MBD patients were reviewed after treatment, the lesion size, morphology, and signal were found no significant change. 1 case corpus callosum infarction patients was reviewed after treatment, the lesion was found slightly narrowed. Conclusion ： MRI can visualize the location and extent of MBD and infarction, It is the most objective reference of the MBD and infarction diagnosis , It can provide di

关 键 词：胼胝体变性 梗死 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学]