Cardiopulmonary,Biochemical and Haematological Effects of the Tiletamine/Zolazepam-Xylazine-Tramadol Combination to Provide Anaesthesia in Miniature Pigs  

作　　者：LU De-zhang FAN Hong-gang JIANG Sheng ZHANG Luan-song MA Kun YU Shi-ming TAN Li-juan WANG Hong-bin 

机构地区：[1]Department of Veterinary Surgery, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, IER. China [2]Department of Veterinary Surgery, College of Veterinary Medicine, Northwest Agricultrue and Forestry University, Yangling 712100, P..R China

出　　处：《Journal of Integrative Agriculture》2012年第8期1340-1346,共7页农业科学学报（英文版）

基　　金：supported by the National Natural Science Foundation of China (30671552 and 30972227)

摘　　要：The objective of this study was to investigate the suitability of tiletamine/zolazepam-xylazine-tramadol combination for miniature pigs. Fourteen Chinese experimental miniature pigs subjected to this study received 3.5 mg tiletamine/zolazepam kg-1 bw, 1.32 mg xylazine kg-1 bw and 1.8 mg tramadol kg-1 bw intramuscularly, as a mixture of the drugs. Cardiopulmonary, biochemical and haematological parameters were recorded before drug administration and after anaesthesia. The combination of the compounds resulted in anaesthesia lasting about 87 min and a satisfactory immobilization for handling. Cardiopulmonary parameters were changed after administration, but there were within biologically acceptable limits. Biochemical and haematological values decreased after drug administration, however, they returned to the baseline at 24 h. At the doses described, tiletamine/zolazepam-xylazine-tramadol combination produced good immobilization in miniature pigs with minimal changes over time in cardiopulmonary, biochemical and haematological parameters.The objective of this study was to investigate the suitability of tiletamine/zolazepam-xylazine-tramadol combination for miniature pigs. Fourteen Chinese experimental miniature pigs subjected to this study received 3.5 mg tiletamine/zolazepam kg-1 bw, 1.32 mg xylazine kg-1 bw and 1.8 mg tramadol kg-1 bw intramuscularly, as a mixture of the drugs. Cardiopulmonary, biochemical and haematological parameters were recorded before drug administration and after anaesthesia. The combination of the compounds resulted in anaesthesia lasting about 87 min and a satisfactory immobilization for handling. Cardiopulmonary parameters were changed after administration, but there were within biologically acceptable limits. Biochemical and haematological values decreased after drug administration, however, they returned to the baseline at 24 h. At the doses described, tiletamine/zolazepam-xylazine-tramadol combination produced good immobilization in miniature pigs with minimal changes over time in cardiopulmonary, biochemical and haematological parameters.

关 键 词：CARDIOPULMONARY tiletamine/zolazepam-xylaxine-tramadol combination ANAESTHESIA miniature pigs 

分 类 号：S859.791[农业科学—临床兽医学] S821[农业科学—兽医学]