体位性高血压的研究进展  

Research advance in orthostatic hypertension

作　　者：邓煦[1] 夏珂[1] 杨天伦[1] 

机构地区：[1]中南大学湘雅医院心内科,长沙410008

出　　处：《临床心血管病杂志》2012年第8期563-565,共3页Journal of Clinical Cardiology

摘　　要：体位性高血压是指体位由卧位转为直立位后收缩压升高至少20mmHg(1mmHg=0.133kPa)。体位性高血压的基本病理生理学被认为涉及交感神经系统的激活,但确切病因尚未清楚,可能引起脑、心血管系统等靶器官的损害。体位性高血压是未来高血压发展发生的一个危险因素,α受体阻滞剂治疗有效,但仍需要更多的研究来证实。Orthostatic hypertension is generally defined as an increase in systolic blood pressure at least 20 mmHg（1 mmHg=0.133 kPa） from lying position to standing position.The underlying pathophysiology of orthostatic hypertension is thought to be related to the activation of the sympathetic nervous system,but the exact etiology is poorly understood.It has been associated with the damage of brain,cardiovascular system and so on.Orthostatic hypertension which can be treated effectively by α adrenoreceptor blockers is a risk in the development of hypertension in the future.However,all these results need more research to be confirmed.

关 键 词：体位性高血压 定义 病理生理学 药物治疗 

分 类 号：R544.1[医药卫生—心血管疾病]