超滤膜富集干姜挥发油的工艺优化研究  

Enriching technology optimization of volatile oil from Zingiberis Rhizoma by ultrafiltration membrane

作　　者：沈洁[1,2] 韩志峰[1,3] 郭立玮[1] 樊文玲[1] 

机构地区：[1]南京中医药大学中药复方分离工程重点实验室,江苏南京210029 [2]南京市第二医院药剂科,江苏南京210002 [3]江苏济川药业集团有限公司,江苏泰州225400

出　　处：《中草药》2012年第8期1526-1530,共5页Chinese Traditional and Herbal Drugs

基　　金：国家科技部"十一五"支撑课题(2006BAI09B07-03)

摘　　要：目的确定超滤膜富集干姜挥发油的最佳工艺。方法以干姜含油水体模拟体系为研究对象,采用正交设计,将稳定膜通量和化学需氧量(COD)截留率的综合值作为评价指标,优化干姜挥发油富集工艺。结果截留相对分子质量7×104的平板超滤膜用于干姜挥发油油水分离的最佳条件:压力0.15 MPa、温度60℃、转速150 r/min;各工艺参数的主次顺序:压力、温度、转速。结论超滤膜富集干姜挥发油的工艺,在中药大生产中具有广阔的应用前景。Objeetive To optimize the enriching technology of volatile oil from Zingiberis Rhizoma by ultrafiltration membrane. Methods The oil-water system ofZingiberis Rhizoma was selected as subject, using orthogonal design, taking stable membrane flux and chemical oxygen demand （COD） retention rate as comprehensive evaluation indexes. Results The optimum conditions of YSM- 7× 10^4 ultrafiltration membrane for oil-water separation ofZingiberis Rhizoma volatile oil were as following： the pressure of 0.15 MPa, temperature at 60℃, and the rotation speed at 150 r/min. The sequence for process parameters was： pressure, temperature, and rotation speed. Conclusion Enriching technology for the volatile oil ofZingiberis Rhizoma by ultrafiltration membrane has a broad applying prospect in large-scale production.

关 键 词：干姜挥发油 超滤膜 油水分离 膜通量 化学需氧量 

分 类 号：R284.2[医药卫生—中药学]