无创通气联合振动排痰治疗COPD急性加重期的研究  

作　　者：朱秀宁 

机构地区：[1]广西壮族自治区梧州市人民医院呼吸内科,543000

出　　处：《当代医学》2012年第24期62-63,共2页Contemporary Medicine

摘　　要：目的探讨无创通气联合振动排痰治疗慢性阻塞性肺疾病(COPD)急性加重期的临床疗效。方法将本院收治的64例COPD急性加重期的患者随机分为试验组和对照组各32例,对照组患者给予常规无创通气及药物治疗,试验组患者在常规治疗基础上增加振动排痰治疗,比较两组患者的pH、PaO2、PaCO2等动脉血气指标及无创通气时间、住院时间。结果试验组患者及对照组患者的动脉血气指标较治疗前均显著改善,但试验组患者改善优于对照组(P<0.05),试验组患者的无创通气时间及住院时间均显著低于对照组([4.1±2.4)d比(8.2±3.1)d,(14.8±6.1)d比(21.8±5.8)d,均P<0.05]。结论无创通气联合振动排痰治疗COPD急性加重期临床治疗效果显著,值得推广应用。Objective To investigate the clinical efficacy of the non-invasive ventilation combined with vibration expectoration treatment for chronic obstructive pulmonary disease （COPD）Methods 64 cases of COPD with acute exacerbations were randomLy divided into experimental and control group. Control group were treated with conventional non-invasive ventilation and drug treatment, experimental group patients were given vibration expectoration treatment in addition. The pH, PaO2, PaCO2, arterial blood gas indicators and non-invasive ventilation and hospitalized time were compared. Results The arterial blood gas indicators was significantly improved after treatment, but the experimental group patients improved better than the control group （P〈0.05）. Non-invasive ventilation and hospitalized time of experimental group was significantly lower than that in the control group （P 〈0.05）. Conclusion Non-invasive ventilation combined with vibration expectoration in treatment of acute exacerbation of COPD has a significant clinical efficacy, which should be widely applied.

关 键 词：慢性阻塞性肺疾病 无创通气 振动排痰 

分 类 号：R563.9[医药卫生—呼吸系统]