Terpenoids from a Chinese Gorgonian Anthogorgia sp. and Their Antifouling Activities  

作　　者：陈达伟 刘东 沈施 程伟 林文翰 

机构地区：[1]State Key Laboratory of Natural and Biomimetie Drugs,Peking University,Beijing 100191,China

出　　处：《Chinese Journal of Chemistry》2012年第7期1459-1463,共5页中国化学（英文版）

摘　　要：Chemical examination of a Chinese gorgonian Anthogorgia sp. resulted in the isolation of seven terpenoids, including two new compounds, an rearranged serrulatane-type diterpenoid anthogorgiene P （1） and a guaiazuenebased terpenoid anthogorgiene Q （2）. Anthogorgiene P （1） contains an unprecedented cubebane nucleus which is rarely found from nature. The structures of new compounds were elucidated on the basis of extensive spectroscopic methods （IR, UV, MS, CD and NMR）. Compound 7 showed potent antifouling activity against the larval settlement of Balanus amphitrite, while 1 and 4 possessed moderate inhibition.Chemical examination of a Chinese gorgonian Anthogorgia sp. resulted in the isolation of seven terpenoids, including two new compounds, an rearranged serrulatane-type diterpenoid anthogorgiene P （1） and a guaiazuenebased terpenoid anthogorgiene Q （2）. Anthogorgiene P （1） contains an unprecedented cubebane nucleus which is rarely found from nature. The structures of new compounds were elucidated on the basis of extensive spectroscopic methods （IR, UV, MS, CD and NMR）. Compound 7 showed potent antifouling activity against the larval settlement of Balanus amphitrite, while 1 and 4 possessed moderate inhibition.

关 键 词：marine gorgonian Anthogorgia sp. TERPENOIDS anthogorgienes P--Q structural elucidation antifouling activity 

分 类 号：O629.61[理学—有机化学] TS952.834[理学—化学]