心率变异性分析指标与AEPI在麻醉深度监测中的相关性研究  

Correlation research between analytical indexes in heart rate variability and auditory evoked potential index during monitoring depth of anesthesia

作　　者：肖霖[1] 

机构地区：[1]江苏大学附属人民医院麻醉科,江苏镇江212002

出　　处：《现代医药卫生》2012年第15期2256-2257,共2页Journal of Modern Medicine & Health

摘　　要：目的探讨全身麻醉(简称全麻)深度监测中反映迷走神经活动性的心率变异性(HRV)分析指标和听觉诱发电位指数(AAI)的变化及相关性。方法择期行全麻手术患者30例,美国麻醉医师协会(ASA)分级Ⅰ～Ⅱ级,测定麻醉诱导前(T0)、诱导插管(T1)、术中(T2)、停药后(T3)各5 min心率(HR)、平均动脉压(MAP)、听觉诱导电位指数(AEPI)、相邻RR间期差的均方根(RMSSD)、高频(HF)和散点图短轴(SD1)变化。结果 T1时HR明显快于T0,MAP明显高于T0(P<0.05);T2的HR明显慢于T0,MAP明显低于T0(P<0.01);T3的HR明显快于T2,MAP明显高于T2(P<0.01)。T1～3的RMSSD、HF、SD1和AEPI明显低于T0,且T2降低更为明显,而T3明显高于T2(P<0.01)。结论反映迷走神经活动性的HRV指标RMSSD、HF、SD1与AEPI在监测麻醉深度时有一定的相关性。Objective To investigate the changes of the analytical parameters of heart rate variability （HRV） reflecting vagus nerve activity and auditory evoked potential index（AEPI） during monitoring depth of general anesthesia and to study their correlation. Methods 30 patients undergoing elective general anesthetic operation with ASA I or Ⅱ were detected and record- ed the parameters such as heart rate （HR）,mean arterial pressure （MAP）,AEPI,RMSSD,high frequency （HF） and SD1 before induction （T0）,intubation （T,）,during operation （T2）,5 min after the cessation of medication （T3）. Results Compared with To, HR at T0 was faster and MAP was higher（P〈0.05 ） ;HR at T2 was significantly slower than that at To and MAP was obviously lower than that at T0（P〈0.01 ） ; HR at T3 was significantly faster than that at T2 and MAP was higher than that at T2（P〈0.01 ）. RMSSD, HF,SD1 and AEPI at T1-3 were significantly lower than those at To,the decrease at T2 was more obvious,but those at T3 were significantly hgher than at T2（P〈O.01 ）. Conclusion RMSSD, HF and SD1 as the HRV indicators reflecting vagus nerve activity show certain correlation with AEPI during monitoring depth of anesthsia.

关 键 词：迷走神经 心率 诱发电位 听觉 麻醉 静脉 心率变异性 听觉诱发电位指数 麻醉深度 

分 类 号：R614.24[医药卫生—麻醉学]