住院肺结核病人耐药情况分析  

Analysis on drug resistance in pulmonary tuberculosis inpatients

作　　者：黄又宁[1] 

机构地区：[1]南宁市第四人民医院,530023

出　　处：《广西医学》2000年第4期692-694,共3页Guangxi Medical Journal

摘　　要：目的 :了解住院肺结核病人的耐药情况。方法 :利用既往住院病人的临床资料回顾性分析和讨论。结果 :原发耐药率和继发耐药率分别为 5 4.6 %和 83.2 % ;原发耐多药率和继发耐多药率分别为 6 %和 5 0 .4%。原发耐药组与药物敏感组在用含吡嗪酰胺 (PZA)的强化短程化疗方案治疗下效果无明显差异 ,而继发耐药及耐多药组的效果则差得多。结论 :抓好初治病例的规范治疗和管理 。Objective:To observe the state of drug resistance in pulmonary tuberculosis inpatients Methods:The data of pulmonary tuberculosis inpatients were reviewed Results:The rates of primary and acquired drug resistance were 54 6%,83 2%;The rates of primary and acquired multi drug resistance were 6%,50 4% Difference was no found between primary durg resistance and sensitive in treatment with PZA The effect was lower in acquired drug resistance and multi drug resistance Conclusion:Drug ressistance might be prevented by a combination of control and rational use of chemotherapy

关 键 词：肺结核 抗痨药 耐药性 抗结核药 

分 类 号：R521.05[医药卫生—内科学] R978.3[医药卫生—临床医学]