实时剪切波弹性成像测量猪离体心脏心肌剪切模量  

Quantification of shear modulus in in vitro porcine myocardium using real-time shear wave elastography

作　　者：汤乔颖[1] 邓又斌[1] 刘琨[1] 张隽[1] 黄媛[1] 孙杰[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院超声科,武汉430030

出　　处：《中华超声影像学杂志》2012年第8期708-710,共3页Chinese Journal of Ultrasonography

摘　　要：目的研究猪离体心脏左室壁心肌剪切模量大小的分布规律。方法取4枚新鲜离体猪心，采用实时剪切波弹性成像技术，在探头方向与左室长轴或短轴平行两种情况下，分别测量各心脏左室前壁心外膜下层、中层和心内膜下层心肌的剪切模量。结果探头方向与左室长轴平行时，测得左室前壁中部心外膜下层、中层、心内膜下层心肌剪切模量分别为（46．04±17．07）kPa，（87．70±29．67）kPa，（115．73±30．04）kPa；探头方向与左室短轴平行时，心外膜下层、中层、心内膜下层心肌剪切模量分别为（78．71±26．48）kPa，（77．08±34．00）kPa，（70．69±41．38）kPa。结论通过实时剪切波弹性成像技术测得的左室壁心外膜下层、中层及心内膜下层心肌剪切模量大小不同，且同一部位心肌在切面不同时剪切模量大小也有差异。Objective To investigate in vitro porcine myocardial shear modulus using real-time shear wave elastography. Methods Shear wave elastography was used on four in vitro porcine hearts. The probe was placed parallel to the long or short-axis of the heart on the anterior wall of the left ventricle, and myocardial shear modulus were measured in subepicardial, middle, subendocardial layers, respectively. Results Shear modulus of subepicardial, middle, subendoeardial myocardium were （46.04 ± 17.07）kPa, （87.70 ± 29.67）kPa, （115.73 ± 30.04）kPa, respectively, when the probe was placed parallel to the long-axis of the heart; whereas those were （78.71 ± 26.48） kPa, （77.08 ± 34.00） kPa, （70.69 ± 41.38） kPa, respectively,when the probe was placed parallel to the short-axis of the heart. Conclusions By using realtime shear wave elastography, the shear modulus values measured in subepieardial, middle, subendocardial myocardium of the left ventricle are different, even myocardium in the same location appears different shear modulus values when the probe orientation are different.

关 键 词：超声心动描记术 心肌 剪切模量 剪切波弹性成像 

分 类 号：R445.1[医药卫生—影像医学与核医学]