40例甲型H1N1流感患者流行病学和临床特征分析  

Analysis epidemiology and clinical characteristics of 40 cases with H1N1 influenza

作　　者：陈蓉[1] 

机构地区：[1]贵州省安顺市人民医院感染性病科,贵州安顺561000

出　　处：《现代预防医学》2012年第16期4264-4265,共2页Modern Preventive Medicine

摘　　要：目的探讨甲型H1N1流感的流行病学及临床特征。方法对收集的40例甲型H1N1流感确诊病例的临床资料、诊治方法及治疗结果进行回顾性分析。结果发病年龄平均(16.5±7.3)岁;发病月份以10月最多,占37.50%;均为本土病例。患病人群以学生为主,占87.50%;临床症状以发热为主,占97.50%;白细胞计数异常者占52.50%;中性粒细胞比例上升者占35.00%;淋巴细胞下降者占52.50%;血小板轻微下降者占15.00%;其中C3稍偏低占7.50%;C反应蛋白均升高占100.00%;CD4+\CD8+明显异常者占30.00%;心肌酶谱升高占37.50%;实变型占57.50%,多发斑片影型占23.50%,间质性肺炎型占15.00%。本组40例患者经治疗,体温恢复正常,流感样症状消失,全部治愈出院。其中体温恢复正常的时间平均(3.4±1.5)d;症状消失时间平均(6.4±2.6)d;住院时间平均(6.5±1.6)d。未出现严重并发症、后遗症;X线片及CT扫描及心肌酶谱检查均恢复正常。结论甲型HlN1流感患者临床表现大部分以发热为主,病情相对较轻,病程较短,预后良好。OBJECTIVE To investigate the HIN1 influenza epidemiology and clinical characteristics. METHODS The collection of 40 cases of influenza H1N1 confirmed cases of chnical data, diagnosis, treatment and treatment results were retrospectively analyzed. RESULTS The mean age was 16.5 ± 7.3 years, and the peak month was October, accounting for 37.50% ; All of them were local residents. The sick people were students, accounting for 87.50%; The clinical symptoms was fever, accounting for 97.50% ; White the blood cell count abnormalities accounted for 52.50%; The number of neutrophils increased and account- ed for 35.00% ; The number of lymphocyte declined and accounted for 52.50% ; A slight decrease was found in platelets, and it accounted for 15.00% ; The C3 was shghtly low and accounted for 7.50% ; C-reactive protein were high and accounted for 100.00% ; CD4＋CD8＋ obvious abnormalities and accounted for 30.00% ; The myocardial enzymes elevated and accounted for 37.50%; The real variant accounted for 57.50%, The multiple spot films accounted for 23.50%, and the interstitial pneumonia type accounted for 15.00%. After treatment, the body temperature of 40 patients returned to normal, and their flu-like symp- toms disappeared, and all of them cured. The average body temperature returned to 3.4 ± 1.5 days, symptoms average was 6.4 ± 2.6 days, and the average length of stay was 6.5 ± 1.6 days. No serious complications and sequelae was found; X-ray and CT scan and check myocardial enzymes were normal. CONCLUSION The most clinical manifestation of influenza H1N1 was fever- based, and the disease was relatively mild, short duration, the prognosis was good.

关 键 词：甲型H1N1流感 流行病学 临床特征 

分 类 号：R373.13[医药卫生—病原生物学]