血浆胆碱酯酶活性检测诊断糖尿病合并高脂血症的临床价值  

Clinical value of plasma cholinesterase activity in the diagnosis of diabetes mellitus complicated with hyperlipidemia

作　　者：李珉珉[1] 卢松耀[1] 郑仕富[1] 

机构地区：[1]暨南大学附属第一医院临床检验中心,广州510630

出　　处：《国际检验医学杂志》2012年第10期1198-1199,共2页International Journal of Laboratory Medicine

基　　金：广东省医学科研基金资助项目(A2010327)

摘　　要：目的探讨糖尿病合并高脂血症患者血浆胆碱酯酶活性的变化及其临床价值。方法检测63例糖尿病合并高脂血症患者、74例单纯糖尿病患者以及100例健康者的血脂水平及血浆胆碱酯酶活性。结果糖尿病合并高脂血症患者血浆胆碱酯酶活性明显高于其他两组(P<0.05);单纯糖尿病患者胆碱酯酶活性则明显低于健康者(P<0.05)。结论胆碱酯酶活性检测有助于疾病的诊断,是反映糖尿病合并高脂血症患者早期并发症的良好指标,具有一定的临床应用价值。Objective To study the changes of plasma cholinesterase activity in patients with diabetes mellitus（DM） complicated with hyperlipidemia and its clinical value.Methods Plasma levels of lipid parameters and cholinesterase activities were detected in 63 DM patients complicated with hyperlipidemia,74 patients with DM alone and 100 healthy subjects.Results The cholinesterase activity in group of DM patients complicated with hyperlipidemia were significantly higher than those in the other two groups（P〈0.05）,however,that in patients with DM alone were significantly lower than in healthy controls（P〈0.05）.Conclusion Detection of cholinesterase activity might contribute to the diagnosis of DM complications,could be a good indicator for the early complications in DM patients with hyperlipidemia,and might has certain value for the clinical diagnosis of this disease.

关 键 词：胆碱酯酶类 糖尿病 高脂血症 诊断 

分 类 号：R587.1[医药卫生—内分泌] R589.2[医药卫生—内科学]