553例生殖道支原体的体外耐药性分析  

In vitro analysis of drug resistance among 533 strains of Mycoplasma isolated from gential tract specimens

作　　者：杨卫萍[1] 

机构地区：[1]江汉大学附属医院检验科,武汉430016

出　　处：《国际检验医学杂志》2012年第12期1448-1449,共2页International Journal of Laboratory Medicine

摘　　要：目的分析江汉大学附属医院生殖道支原体感染的状况及药敏情况,为临床合理用药提供参考。方法对2009年1月至2011年1月期间的533例阴道分泌物标本采用法国生物梅里埃支原体IST试剂盒,进行支原体培养、鉴定并进行体外药物敏感试验。结果送检标本中支原体培养总阳性率为72.98%,其中解脲脲原体(Uu)阳性率为40.90%,耐药率由高到低依次为环丙沙星、氧氟沙星、红霉素、阿奇霉素、克拉霉素、四环霉素、交沙霉素、多西环素、原始霉素;人型支原体(Mh)阳性率为2.06%,耐药率由高到低依次为红霉素、阿奇霉素、环丙沙星、克拉霉素、氧氟沙星、四环霉素、交沙霉素、多西环素、原始霉素;Uu与Mh混合感染阳性率30.02%,其耐药率由高到低依次为环丙沙星、氧氟沙星、红霉素、克拉霉素、阿奇霉素、交沙霉素、四环素、原始霉素、多西环素。结论支原体的耐药性在不同地区表现不同,临床应参照药敏试验结果选用抗菌药治疗患者。Objective To investigate the infection situation and drug susceptibility of Mycoplasma in this hospital for reasonable medication in clinics.Methods 533 cases of vaginal secretions were detected by using Mycoplasma diagnostic kits of Mycoplasma IST（French） Co.LTD to perform the Mycoplasma culture,identification and drug susceptibility test from Jan.2009 to Jan.2011.Results The positive rate of Mycoplasma culture was 72.98%.The positive rate of Ureaplasma urealyticum（Uu） was 40.90%,and antibiotics,ranged by drug resistance rate from high to low,were ciprofloxacin,ofloxacin,erythromycin,azithromycin,clarithromycin,tetracycline,josamycin,doxycycline and pristinamycin.The positive rate of Mycoplasma hominis（Mh） was 2.06%,and antibiotics,ranged by drug resistance rate from high to low,were erythromycin,azithromycin,ciprofloxacin,clarithromycin,ofloxacin,tetracycline,josamycin,doxycycline and pristinamycin.The positive rate of mixed infection of Uu and MH was 30.02%,and antibiotics,ranged by drug resistance rate from high to low,were ciprofloxacin,ofloxacin,erythromycin,clarithromycin,azithromycin,josamycin,tetracycline,pristinamycin and doxycycline.Conclusion The drug resistance of Mycoplasma might be different between various regions,and antibiotics should be prescribed according to the results of antibiotic susceptibility test.

关 键 词：支原体属 生殖道 耐药性 

分 类 号：R446.5[医药卫生—诊断学]