泌尿生殖道标本衣原体、支原体检测及药敏分析  

Resistance analysis of chlamydia and mycoplasma isolated from genitourinary track samples

作　　者：刘惠芬 林定忠[2] 苏兰妹[2] 袁花艳[2] 段先兵 

机构地区：[1]广东省惠州市惠城区桥东街道办事处社区卫生服务中心,516002 [2]广东省惠州市惠阳区人民医院,516211

出　　处：《国际检验医学杂志》2012年第13期1601-1602,共2页International Journal of Laboratory Medicine

摘　　要：目的探讨泌尿生殖道标本解脲支原体(Uu)、人型支原体(Mh)及沙眼衣原体(Ct)的检出率及Uu对常用抗菌剂的耐药情况。方法回顾性统计分析2010年1月至2011年12月送检的2967份泌尿生殖道标本Uu、Mh、Ct的检出率及Uu的药敏实验结果。结果 1235份男性标本中,Uu、Mh、Ct的检出率分别为15.5%、2.6%、3.4%;1732份女性标本,Uu、Mh、Ct的检出率分别为37.6%、7.6%、9.5%,Uu对氟喹诺酮类抗菌剂的敏感率最低,环丙沙星30.6%,左氧氟沙星32.1%;多西环素、交沙霉素、阿奇霉素、美满霉素敏感率最高,分别为97.9%、97.6%、94.7%、94.8%;对其余6种抗菌剂敏感率51.0%～69.3%。结论泌尿生殖道衣原体、支原体的感染相当普遍,对常用抗菌剂产生不同程度的耐药,临床应引起高度重视并进行支原体培养及药敏实验,根据药敏结果合理选用抗菌剂,从而最大限度地控制耐药菌株的产生。Objective To investigate the isolation rate of Chlamydia trachomatis（Ct）,Ureaplasma urealyticum（Uu） and Mycoplasma hominis（Mh） in genitourinary tract samples and the drug resistance rate of Uu.Methods Isolation rates of Uu,Mh and Ct in 2 967 genitourinary samples and results of drug susceptibility test of Uu from 2010 to 2011 were retrospective statistical analyzed.Results In 1 235 male samples,the isolation rates of Uu,Mh and Ct were 15.5%,2.6% and 3.4%,those in 1 732 female samples were 37.6%,7.6% and 9.5%.Sensitivity rate of Uu to fluoroquinolone was the lowest,those to ciprofloxacin,levofloxacin,doxycycline,josamycin,azithromycin,minocycline were 30.6%,32.1%,97.9%,97.6%,94.7% and 94.8%,and those to other six antibiotics were from 51.0% to 69.3%.Conclusion Genitourinary tract infection of chlamydia and mycoplasma might be quite common,and with different degree of resistance to frequently used antibiotics.More attention should be paid to culture and drug susceptibility test for rational use of antibiotics and maximizing the prevalence of drug resistant strains.

关 键 词：沙眼衣原体 解脲支原体 人型支原体 泌尿生殖道 

分 类 号：R446.5[医药卫生—诊断学]