天寿液对Ⅱ型糖尿病患者细胞膜活性和能量代谢的影响  

Study of Tian-Shou Liquor on Activity of Cell Membrane and Energy Metabolism in Diabetes Mellitus

作　　者：查良伦[1] 沈自尹[1] 张萍 龚志铭 陶鸿根 余环 

机构地区：[1]上海医科大学中西医结合研究所,上海200040 [2]华山医院中草药制剂室 [3]上海医科大学化学教研室

出　　处：《中西医结合杂志》1990年第8期455-457,共3页

摘　　要：用中药天寿液治疗Ⅱ型糖尿病患者65例半年,患者红细胞膜脂区流动性和血清 HDL_2-C 水平明显增加,血清胆固醇和血糖浓度则显著下降,与治疗前比较,差异均具有显著性意义。并对糖尿病发病机理及中药治疗意义进行了探讨。The research of Chinese medicine Tian-Shou Liquor(TSL)on the fluidity,of the membrane lipid regions of intact erythrocyte(showed by microviscosity,(?)),the activity of sodium pump of red cell, the plasma lipid level and sugar concentration in 65 cases of diabetes mellitus were determined before the treatment and a half year after the treatment.82 normal cases were studied as a control group.The results showed that the diabetic group had an obviously lower fluidity of erythrocyte membrane and activity of sodium pump of red cell than those of normal groups(P<0.001).The microviscosity of 27 diabetes patients treated by TSL were markedly decreased when compared with before treatment(P<0.01).The changes of activity of sodium pump had no significant difference before and after treatment with TSL.According to the determination of plasma lipid,it was discovered that the total cholesterol concentration and HDL_2-C level in diabetes patients were obviously higher and lower than those of normal groups respectively(p<0.001).One half Year after treatment,the patients' cholesterol concentration had significantly decreased,but the HDL_2-C level were markedly raised by means of comparison between before and after treatment.Blood sugar concentration of 43 cases with TSL treatment decreased evidently(P<0.001).

关 键 词：天寿液 糖尿病 细胞膜活性 

分 类 号：R587.105[医药卫生—内分泌]