超声组织多普勒在监测心脏移植急性排异反应中的价值  

Echocardiography on Acute Rejection after Heart Transplantation

作　　者：谷孝艳[1] 何怡华[1] 李治安[1] 薛超[1] 潘泽雁[1] 韩建成[1] 张烨[1] 

机构地区：[1]首都医科大学附属北京安贞医院超声诊断科,北京市100029

出　　处：《中国超声医学杂志》2012年第8期726-729,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的与心内膜心肌活检对比,探讨组织多普勒成像在监测心脏移植术后急性排异反应方面的价值。方法根据心肌活检结果将心脏移植患者分为3组:0级为B组,Ⅰ级为C组,≥Ⅱ级为D组;设30例志愿者为A组。对所有研究对象进行组织多普勒参数测量,数据进行组间比较。结果与对照A组相比,心脏移植患者的组织多普勒参数值均明显降低(P<0.05)。B组与C组比较:数值没有明显变化。发生排异反应的D组与B组、C组比较:Em峰、Sm峰、舒张早期时间Tem减低具统计学意义(P<0.05)。结论超声组织多普勒成像能在早期敏感地检测出Ⅱ级或大于Ⅱ级急性排异反应,可以作为监测心脏移植术后急性排异反应的筛查方法,从而减少心内膜心肌活检次数。Objective To observe the acute rejection reaction after heart transplantation （HT） by Tissue Doppler imaging （TDI）, comparing with pathology to evaluate the value of Tissue Doppler imaging technique in detecting acute rejection reaction after heart transplantation. Methods 30 endomyocardial biopsies were taken from 25 HT patients. 30 age-matched studies comprised group A. TDI studies were obtained in each patient, and Data were compared Among groups. Results Tissue Doppler imaging showed that peak early diastolic wall motion velocity （Era）, Peak late diastolic wall motion velocity（Am）, peak systolic wall motion velocity （Sin） and early diastolic time（Tern） decreased significantly in group D compared to B and C. There was not significant difference between group B and C. Conclusions Echocardiography especially Tissue Doppler imaging is an effective and sensitive technique for the detection of acute rejection with grade≥Ⅱ after cardiac transplantation.

关 键 词：超声心动图 组织多普勒成像 心脏移植 急性排异反应 

分 类 号：R654.2[医药卫生—外科学] R540.45[医药卫生—临床医学]