胎儿颜面部角度三维超声测量在诊断小下颌畸形中的应用  

The Application of Fetal Facial Angle Measurement with Three-dimensional Ultrasound in the Diagnosis of Micrognathia

作　　者：杨姝[1,2] 蔡爱露[1] 辛忠秋[3] 李婷[1] 刘炜 王冰[1] 郭淑香[1] 

机构地区：[1]中国医科大学附属盛京医院 [2]沈阳市妇婴医院,沈阳市110004 [3]黑龙江省大庆油田总医院 [4]辽宁省抚顺市矿物局总医院

出　　处：《中国超声医学杂志》2012年第8期751-753,共3页Chinese Journal of Ultrasound in Medicine

基　　金："十一五"国家科技支撑计划项目(No.2006BAI05A04)

摘　　要：目的研究胎儿颜面部角度孕期发育规律,探讨测量胎儿颜面部角度在产前诊断小下颌畸形中的应用价值。方法选择20～36孕周正常胎儿188例,应用经腹三维超声测量胎儿颜面部角度,采用SPSS 13.0软件分析颜面部角度正常值范围,Person相关系数(r)评估胎儿颜面部角度与孕周相关性;对比小下颌畸形胎儿颜面部角度与正常组差异。结果 20～36孕周正常胎儿颜面部角度与孕周无相关性,r=0.001,P=0.757。胎儿颜面部角度均值是62.37°,标准差为6.23°。颜面部角度小于49.9°诊断为小下颌畸形。6例小下颌畸形胎儿颜面部角度均小于49.9°。结论应用三维超声检测胎儿颜面部角度,为产前诊断小下颌畸形提供一种客观定量的检测方法。Objective To study the development pattern of fetal facial angle during pregnancy, and the application of fetal facial angle measurement in diagnosing micrognathia in prenatal. Methods 188 normal fetuses in 20-36 gestational weeks were select, the fetal facial angle were measured with three-dimensional ultrasound, The range of normal values of fetal facial angle was analysed using SPSS 13.0 software. Person correlation coefficient （r） was used to assess the correlation between fetal facial angle and the gestational weeks; the difference of fetal facial angle were contrast between mierognathia and normal group. Results There was negativecorrelation between the normal fetal facial angle and the gestational weeks（r= 0. 001, P=0. 757）. Average value of the normal fetal facial angle is 62.37°, SD 6.23°, fetal facial angle less than 49.9° was diagnosed micrognathia. The 6 micrognathia fetal facial angle were all less than 49.9°. Conclusions Detection of the fetal facial angle with three dimensional ultrasound was an objective quanti tative detection method for diagnosis mierognathia in prenatal.

关 键 词：胎儿 小下颌畸形 颜面部角度 三维超声 

分 类 号：R445.1[医药卫生—影像医学与核医学] R714.5[医药卫生—诊断学]