静脉高氧液治疗对颅脑损伤患者预后的影响  

Effect of venous hyperoxia liquid on the prognosis of patients with traumatic brain injury

作　　者：卢东文[1] 陆小妮[1] 罗前颖[1] 

机构地区：[1]右江民族医学院附属医院神经外科,广西百色533000

出　　处：《右江医学》2012年第4期458-460,共3页Chinese Youjiang Medical Journal

基　　金：百色市科技项目[百科计字(2009)8号]

摘　　要：目的探讨静脉高氧液治疗对颅脑损伤患者预后的影响。方法将126例颅脑损伤患者随机分为观察组和对照组各63例。对照组按脑损伤常规治疗,观察组在对照组的基础上给予高氧液治疗;分别观察两组治疗前、治疗后的血氧饱和度(SpO2)、神经功能缺损情况,观察两组1周内的死亡率。结果治疗第1d、3d、7d观察组患者的SpO2显著优于对照组(P均<0.01);治疗第7d神经功能缺损的改善明显著优于对照组(P<0.01);观察组1周内死亡率显著低于对照组(P<0.05)。结论静脉高氧液治疗能提高颅脑损伤患者的血氧饱和度,促进患者神经功能的恢复,降低死亡率,改善患者的预后。Objective To investigate the effect of venous hyperoxia liquid on the prognosis of patients with traumatic brain injury. Methods 126 cases with traumatic brain injury were randomly divided into the observation group and the control group with 63 cases in each group. The control group was given the conventional brain injury treatment,while the observation group was given the venous hyperoxia liquid treatment on the basis of conventional treatment. The oxygen saturation （SpO2） and the neurologic impairment of the two groups were observed both before and after the treatment. The mortality rates of both groups were recorded within one week. Results In the treatment of the first day, third day and seventh day, the SpO2 of the observation group was higher than that of the control group（ P 〈0.01）. The improvement of the neurologic impairment for the observation group was also better than that of the control group（ P 〈0.01）. Within one week, the observation group had lower mortality rate than the control group （ P 〈 0. 0 5 ） . Conclusion The venous hyperoxia liquid can improve the SpO2 , promote the recovery of nervefunction, reduce the mortality rate and improve the prognosis for patients with the traumatic brain injury.

关 键 词：颅脑损伤 静脉高氧液 预后 

分 类 号：R651.150.5[医药卫生—外科学]