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作 者:夏承来[1] 黄汉辉[1] 吴仲洪[1] 卢泳妍[1]
机构地区:[1]广州医学院第三附属医院药学部,广州510150
出 处:《中国医院用药评价与分析》2012年第7期613-615,共3页Evaluation and Analysis of Drug-use in Hospitals of China
基 金:广东省人口与计划生育委员会项目(20110266)
摘 要:目的:调查我院创伤外科抗菌药物应用情况,并进行合理性分析,以提高合理用药水平。方法:随机抽取我院创伤外科2011年8—12月出院患者病历共294份,根据《抗菌药物临床应用指导原则》对抗菌药物应用进行评价。结果:294例病历中,应用抗菌药物的病历为158例(其中Ⅰ类切口手术病历99例、Ⅱ类切口手术病历42例、非手术病历17例),抗菌药物使用率为53.7%。在应用抗菌药物的158份病历中,其中送检病例为19例,送检率为12%。294例病历中,手术病历为277例(Ⅰ类切口手术病历235例、Ⅱ类切口手术病历42例)、非手术病历为17例,手术病历抗菌药物平均使用时间为3 d。使用频率较高的抗菌药物是第2、3代头孢菌素和氟喹诺酮类。结论:我院创伤外科抗菌药物的应用存在一些不合理的现象,用药时间长、手术预防用药选用档次高及病原学检查不够重视是主要特点。OBJECTIVE: To investigate the utilization of antibiotics in traumatic patients of our hospital and analyze its rationality so as to improve the rational drug use level.METHODS: A total of 294 medical histories of patients who had been discharged from the traumatology department of our hospital were randomly sampled during Aug.-Dec.of 2011 for evaluation regarding the utilization of antibiotics in accordance with the "Guiding principle for the clinical application of antibacterials".RESULTS: Of the 294 cases,158(53.7%) were treated with antibiotics,with 99 undergoing type Ⅰ incision operations and 42 cases type Ⅱ incision operations,and 17 didn’t undergoing operation.Of the 158 antibiotic receivers,19(12%) received etiological test.Of the total 294 patients reviewed,277 underwent operations,with 235 undergoing type Ⅰ incision operations and 42 type Ⅱ incision operations,and 17 didn’t undergoing operation.The patients undergoing operation received antibiotics for an average of 3 days.The second and the third generation cephalosporins and quinolones took the lead on the list of DDDs.CONCLUSION: The utilization of antibiotics in the traumatic patients in our hospital was far from rational and which was characterized by prolonged administration duration,high level of drugs in preventive medication,and lack of attention to the etiology test.
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