慢性阻塞性肺疾病患者两种雾化吸入疗法的临床效果对比研究  

Clinical effects comparison and research of two aerosol inhalation methods for chronic obstructive pulmonary disease patients

作　　者：伍爱芳[1] 江月娥[1] 段红萍[1] 伍海英[1] 李满莲[1] 

机构地区：[1]广东省肇庆市第一人民医院呼吸内科,526021

出　　处：《国际护理学杂志》2012年第8期1376-1378,共3页international journal of nursing

摘　　要：目的比较两种雾化吸入疗法对慢性阻塞性肺疾病（COPD）患者动脉血气分析及临床症状体征的影响。方法将90例COPD患者随机分为压缩组和氧驱组各45例，用相同剂量的硫酸沙丁胺醇雾化吸入溶液加生理盐水，分别采用压缩空气雾化吸入和氧驱雾化吸入，雾化吸入前后分别抽取动脉血行血气分析检查，同时监测患者临床症状体征的变化。结果两组患者雾化吸入前后比较，Pa02值及SaO：值均升高，两组同期比较无显著性差异（P〉0．05）；PaCO：值，压缩空气吸人组降低（P〈0．05），而氧驱雾化吸入组无明显变化（P〉0．05），两组同期比较有显著性差异（P〈0．05）；两组雾化吸入后临床症状体征比较，差异无显著性意义（P〉0．05）。结论压缩空气雾化吸人及氧驱雾化吸入均适用于COPD患者，但对于COPD合并II型呼吸衰竭的患者，压缩空气雾化吸入疗法优于氧驱雾化吸入。Objective To compare the effects of two ways of aerosol inhalation to arterial blood gas analysis and clinical symptoms and signs of patients with COPD. Methods A total of 90 patients with COPD were randomly divided into two groups, 45 per group, using compressed air aerosol inhalation and oxygen aerosol inhalation separately, with the same dose of salbutamol sulfate aerosol inhalation solution and normal saline, before and after that, getting arterial blood samples to analyze blood gas, and monitoring the clinical symptoms and signs of patients at the same time. Results The PaO2 and SaO2 value of both groups of patients were increased after aerosol inhalation. There was no significant difference between the two groups （ P 〉 0. 05 ） . The PaCO2 value of the compressed air group was decreased （ P 〈 0. 05 ）, and had no significant change in the oxygen group （P 〉 0. 05 ） . There was significant difference between the two groups （P 〈 0. 05 ） . Clinical symptoms and signs had no significant difference between the two groups （ P 〉 0.05 ） . Conclusions Compressed air aerosol inhalation and oxygen aerosol inhalation are both suitable for patients with COPD. However, for COPD patients with type - II respiratory failure, compressed air aerosol inhalation is better than oxygen aerosol inhalation.

关 键 词：慢性阻塞性肺疾病 压缩空气雾化吸入 氧驱雾化吸入 

分 类 号：R472[医药卫生—护理学]