糖尿病足感染细菌培养及相关因素分析  

Analysis of infected with the bacterial culture and correlative factor of diabetic foot

作　　者：温志刚[1] 郑亮[1] 林小玲[1] 

机构地区：[1]广东省江门市中心医院,529000

出　　处：《临床合理用药杂志》2012年第25期17-18,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的分析糖尿病足患者感染细菌常见类型及耐药情况,探讨可能影响愈后的相关因素。方法采集糖尿病足患者73例病灶的分泌物做细菌培养和药物敏感试验,同时查糖化血红蛋白并行下肢血管彩色多普勒超声。结果 73例患者中,细菌培养阳性59例,阳性率为80.8%;共得到70株菌株,革兰阳性(G^+)球菌32株(45.7%),耐药菌株22株(68.8%);革兰阴性(G^-)杆菌34株(48.6%),耐药菌株6株(17.6%)。糖尿病足D期患者细菌混合感染率为19.6%明显高于B期的7.4%,差异有统计学意义(P<0.05)。糖化血红蛋白均值为(9.07±2.18)%。结论对糖尿病足患者应根据细菌培养结果合理选用抗生素;同时重视血糖控制、积极改善局部血运才能真正改善糖尿病足患者的预后。Objective To analyse infection common bacterial type and resistance in patient with diabetic foot,to ex- plore the related factor of may affect the prognosis. Methods Collected 73 cases of diabetic foot lesions secretions for bacterial culture and drug sensitivity tests at the same time check the glycosylated hemoglobin parallel the lower limb vascular color Doppler ultrasound. Results In 73 cases patients, the bacterial culture positive in 59 cases, the positive rate was 80.8% ; A total of 70 strains of Gram-positive （G ＋ ） bacilli 32, （45.7%）, drug-resistant strains 22 （68.8 % ） ;Gram-negative （G-） bacil- li 34（48. 6% ） ,drug-resistant strains 6（ 17.6% ）. Bacterial mixed infection rate of diabetic foot stage D patients was 19.6% significantly higher than that of stage B （7.4%）, the difference was statistically significant （P 〈 0.05 ）. Glycosylated hemoglo- bin mean was （9.07 ＋ 2. 18 ） %. Conclusion Patient with diabetic foot should be based on bacterial culture results of the ra- tional use of antibiotics ; While focusing on blood sugar control, and actively improve the local blood supply in order to really improve the prognosis of patient with diabetic foot.

关 键 词：糖尿病足 细菌培养 药物敏感性 相关因素 

分 类 号：R587.2[医药卫生—内分泌]