5-甲氧基-4-硝基邻苯二胺的合成新工艺  

Novel Synthesis of 5-methoxy-4-nitro-1,2-phenylenediamine

作　　者：金宁人[1] 刘伟利[1] 谢品赞[1] 胡燕红 张建庭[1] 

机构地区：[1]浙江工业大学化材学院,浙江杭州310014 [2]鼎龙化工集团公司,浙江杭州310005

出　　处：《广东化工》2012年第9期66-68,共3页Guangdong Chemical Industry

基　　金：江苏科技支撑计划项目(BE2011129)

摘　　要：系统地研究了用于制备高分子新单体2,5-二氨基-6-羟基苯并咪唑(DAHBI)的关键中间体5-甲氧基-4-硝基邻苯二胺(MNPDA)的合成,获得了IR和MS定性合格的目标产物。结果表明:以1,5-二氯-2,4-二硝基苯(DCDNB)为原料经单氨解和醇解二步反应先制得5-甲氧基-2,4-二硝基苯胺(MDNA),再经多硫化钠选择还原合成MNPDA的路线,经工艺优化后,可获得纯度为98.9%,总收率42.2%的MNPDA。为结构改性高聚物的创新研发与性能研究提供物质基础。Novel synthesis of 5-methoxy-4-nitro-1,2-phenylenediamine（MNPDA）,a key intermediate for preparing polymer monomers 2,5-diamino-6-hydroxy benzimidazole（DAHBI）,was systematically studied,target product was obtained and confirmed by IR and MS.The results showed that： the synthesis route of MNPDA included two step reaction of preparing 5-methoxy-2,4-dinitroaniline（MDNA） by mono-ammonolysis and alcoholysis from 1,5-dichloro-2,4-dinitrobenzene（DCDNB）,and selective reduction reaction of the MDNA using sodium sulfide.After the process optimization,prepared MNPDA has the purity above 98.9 % and the total yield of 42.2 %,which provided material basis for the innovation research and performance studies of molecular structure modified polymers.

关 键 词：5-甲氧基-4-硝基邻苯二胺 5-甲氧基-2 4-二硝基苯胺 1 5-二氯-2 4-二硝基苯 结构改性高聚物 

分 类 号：TQ316.342[化学工程—高聚物工业]