重庆市南岸区2009～2010年感染性腹泻病原菌监测及药敏结果分析  

Distribution and drug resistance surveillance of diarrheal pathogenic bacteria in Nan′an district,Chongqing from 2009-2010

作　　者：许磊[1] 曾德唯[1] 甘忠志 邓辉[1] 

机构地区：[1]重庆市南岸区疾病预防控制中心,400067

出　　处：《重庆医学》2012年第23期2402-2404,共3页Chongqing medicine

摘　　要：目的监测重庆市南岸区腹泻病患者中,病原菌感染情况及对抗菌药物的敏感情况,为制定预防措施和临床治疗提供参考依据。方法收集重庆市南岸区哨点医院的腹泻患者粪便标本,进行肠道致病菌检测,对检出的金黄色葡萄球菌和沙门菌进行药敏试验。结果 735份腹泻患者粪便中检出肠道致病菌81株,检出率为11.02%,其中金黄色葡萄球菌所占比例最高,其次是沙门菌。对29株金黄色葡萄球菌进行了药敏实验,其中青霉素耐药率达100%,20.68%对克林霉素耐药,对苯唑西林、四环素耐药率均为13.79%;对23株沙门菌进行了药敏实验,其中甲氧苄氨嘧啶耐药率达39.10%,氨苄西林耐药率达26.09%,哌拉西林耐药率达17.39%。结论南岸区腹泻病患者以金黄色葡萄球菌、沙门菌感染为主。金黄色葡萄球菌、沙门菌对多种抗菌药物耐药,应规范临床用药,加强细菌耐药性监测。Objective To investigate Epidemiological characteristics of diarrheal phthogenic bacteria and their drug resistance,so as to provide a scientific basis for the prevention and control and clinical rational use of antibiotics. Methods To collect diarrhea pa- tients stool from Sentinal in Nan＇an district and to detect intestinal bacteria,using the detection of Staphylococcus aureus and Sal monella in drug sensitivity rest. Results The drug resistance rate of 29 Staphylococcus aureus to penicillin was 100% ,to clindamy cin was 20.68% ,to oxacillin was 13, 79% ,to acheomycin was 13.79%. The drug resistance rate of 23 Salmonella to trimethoprim was 39.10 % ,to ampicillin was 26.09 %, to Piperacillin was 17.39 %. Conclusion Staphylococcus aureus and Salmonella are main pathogenic bacteria of diarrhea patients in Nan＇ an district, which had various resistance to antibiotics. Drug resistant monitor and antimicrobial rational use should be paid attention.

关 键 词：腹泻 沙门菌 金黄色葡萄球菌 耐药性 

分 类 号：R446.5[医药卫生—诊断学]