硅胶键合的N-丙基三亚乙基四胺氨基磺酸作为可回收固体酸催化剂催化合成2-氨基-4,6-二芳基烟腈(英文)  

Synthesis of 2-Amino-4,6-diarylnicotinonitriles Using Silica-Bound N-Propyl Triethylenetetramine Sulfamic Acid as a Recyclable Solid Acid Catalyst

作　　者：Khodabakhsh NIKNAM Abbas JAMALI Marzieh TAJADDOD Abdollah DERIS 

机构地区：[1]Department of Chemistry,Faculty of Sciences,Persian Gulf University,Bushehr 75169,Iran

出　　处：《催化学报》2012年第8期1312-1317,共6页

基　　金：supported by Persian Gulf University Research Council(PGU/FS/6-1/1390/705)

摘　　要：A simple and efficient procedure for the preparation of silica-bound N-propyl triethylenetetramine sulfamic acid(SBPTETSA) by the reaction of silica-bound N-propyl triethylenetetramine(SBPTET) with chlorosulfonic acid in chloroform is described.Silica-bound N-propyl triethylenetetramine sulfamic acid was employed as a recyclable catalyst for the synthesis of 2-amino-4,6-diarylnicotinonitriles from the multi-component reaction of an acetophenone derivative,an aromatic aldehyde,malononitrile,and ammonium acetate under solvent-free conditions at 100 °C.The heterogeneous catalyst was recycled for five consecutive runs in the optimized multi-component reaction of 4-chloroacetophenone,4-chloroenzaldehyde,malononitrile,and ammonium acetate without significant loses to its catalytic activity.A simple and efficient procedure for the preparation of silica-bound N-propyl triethylenetetramine sulfamic acid（SBPTETSA） by the reaction of silica-bound N-propyl triethylenetetramine（SBPTET） with chlorosulfonic acid in chloroform is described.Silica-bound N-propyl triethylenetetramine sulfamic acid was employed as a recyclable catalyst for the synthesis of 2-amino-4,6-diarylnicotinonitriles from the multi-component reaction of an acetophenone derivative,an aromatic aldehyde,malononitrile,and ammonium acetate under solvent-free conditions at 100 °C.The heterogeneous catalyst was recycled for five consecutive runs in the optimized multi-component reaction of 4-chloroacetophenone,4-chloroenzaldehyde,malononitrile,and ammonium acetate without significant loses to its catalytic activity.

关 键 词：三乙烯四胺 固体酸催化剂 氨基磺酸 氧化硅 可回收 丙基 合成 苯乙酮衍生物 

分 类 号：TQ246.7[化学工程—有机化工]