糖尿病患者的视觉诱发电位  

Visual evoked potentials of diabetes mellitus

作　　者：任炼儿[1] 郎林福[2] 

机构地区：[1]浙江省中医院眼科,杭州310006 [2]浙江省人民医院眼科研究室

出　　处：《中国中医眼科杂志》2000年第3期133-135,共3页China Journal of Chinese Ophthalmology

摘　　要：目的　探讨糖尿病患者的视觉诱发电位在糖尿病视网膜病变检查中的应用价值。方法　对 35例 (70只眼 )糖尿病患者及 2 4例 (2 8只眼 )正常人进行了VEP的P1 0 0 、N2 、P2 波型的检查和比较分析。结果　P1 0 0 潜时在增殖型糖尿病视网膜病变中有明显延长 (P <0 0 1 ) ;P1 0 0 振幅在未发生糖尿病视网膜病变的患者中已有明显改变 (P <0 0 1 ) ,并随病情进展而进一步降低。N2 和P2 振幅在未发生糖尿病视网膜病变患者中已有降低 (N2 AP <0 0 5 ;P2 AP <0 0 1 )。在不同程度的糖尿病视网膜病变组之间比较差异无显著性 (均P >0 0 5 ) ;N2 和P2 潜时各组间差异无显著性。结论　P1 0 0 潜时、振幅、N2 和P2 振幅对糖尿病视网膜病变的检测具有临床价值 ,P1 0 0 、N2 和P2OBJECTIVE To investigate clinical applicable value of visual evoked potentials(VEP) in examinations of the patients with diabetes mellitus for diabetic retinopathy. METHODS P 100 、N 2、P 2 of VEP were examined in 35 patients (70 eyes ) with diabetic mellitus and 24 volunteers ( 28 eyes ) without retinopathy. The data of VEP were compared and analyzed. RESULTS Latency of P 100 was delayed obviously in the patients with proliferative diabetic retinopathy ( P <0 01). A visible change of amplitude of P 100 was found in the patients with diabetes mellitus without retinopathy ( P <0 01), and the amplitudes were reduced further. There was a reduction of amplitudes of N 2 and P 2 in the patients without diabetic retinopathy (N 2A P <0 05;P 2A P <0 01).The difference was not statistics significant among various stages of diabetic retinopathy ( P >0 05). CONCLUSION Detection of latency and amplitude of P 100 , amplitude of N 2 and P 2 is clinical valuable and the amplitudes P 100 , N 2 and P 2 could be available coindication in diagnosis of early phase of diabetic retinopathy.

关 键 词：糖尿病视网膜病变 视觉诱发电位 

分 类 号：R587.2[医药卫生—内分泌] R770.43[医药卫生—内科学]