变应性鼻炎患者血清与鼻分泌物中粉尘螨sIgE的相关性研究  

Study of the relationship between sIgE of dust mite in serum and nasal secretion of allergic rhinitis

作　　者：施秋梅[1] 陈建军[1] 项济生[1] 舒宏[1] 檀慧芳[1] 

机构地区：[1]同济医科大学附属协和医院耳鼻咽喉科,武汉430022

出　　处：《临床耳鼻咽喉科杂志》2000年第8期342-346,共5页Journal of Clinical Otorhinolaryngology

摘　　要：目的 :探讨常年性变应性鼻炎患者血清与鼻分泌物中粉尘螨 s Ig E( specific Ig E)的相关性。方法 :收集常年性变应性鼻炎可疑患者血清及鼻分泌物 ,测定其中粉尘螨 s Ig E并进行分析。结果 :血清及鼻分泌物中 ,粉尘螨 s Ig E浓度及其自然对数值间具有明显的相关性。结论 :测定可疑患者血清中粉尘螨 s Ig E可较好反映局部过敏程度 ;对部分局部表现和血清 s Ig E中情况不符者 ,测鼻分泌物 s IgObjective: To search for the relationship between specific IgE of Dermatophagoides farinae in the serum and that in the local secretion of perennial allergic rhinitis patients.Method:The serum and nasal secretion of suspected patients were collected,then test the concentration of mite sIgE in the serum as well as that in the secretion.The results were analyzed at last. Result: The relationship of mite sIgE concentration and logarithm of the concentration between the serum and the local secretion is obvious(relative coefficient is 0.675 and 0.846 respectively.) Conclusion:Dertermining the Dermatophagoides farinae sIgE in the serum can reflect the local condition of suspected patients fairly well. While for some patients whose local condition is not according to the serum sIgE, testing the local sIgE is necessary to get a correct diagnose.

关 键 词：变应性鼻炎 鼻粘膜 尘螨 免疫球蛋白E 

分 类 号：R765.2[医药卫生—耳鼻咽喉科]