胃肠通过时间测定在糖尿病患者中的临床应用分析  

The measurement and its clinical significance of gastrointestinal transit time in patients with diabetes of functional disturbance of gastrointestinal tract

作　　者：张海峰[1] 杨清[1] 毛於安[1] 

机构地区：[1]新疆医科大学第六附属医院消化科,乌鲁木齐830002

出　　处：《新疆医科大学学报》2012年第8期1056-1058,共3页Journal of Xinjiang Medical University

基　　金：新疆维吾尔自治区科技支疆项目(200991127)

摘　　要：目的探讨应用不透X线标志物测定2型糖尿病(T2DM)患者的胃肠通过时间的临床意义。方法测定173例糖尿病伴便秘及腹泻患者的胃肠通过时间(GITT),乳果糖氢呼气试验(LHBT)测定口-盲通过时间(OCTT)。结果糖尿病伴便秘患者液体排空时间(OCTT)为(114.7±19.6)h,其中异常占27.1%(28/103),延长占18.4%(19/103),缩短占8.7%(9/103);糖尿病伴腹泻患者液体排空时间(OCTT)为(110.5±15.6)h,其中异常占22.8%(16/70),10例OCTT缩短,6例OCTT延长。糖尿病患者TGITT异常占67.05%(116/173),结肠通过时间异常占33.53%(58/173)。结论不透X线标志物测定胃肠通过时间简单易于操作;对糖尿病伴胃肠功能紊乱患者的诊治评估具有临床价值。Objective To explore the clinical significance of gastrointestinal transit time（GITT） in type 2 diabetes mellitus（T2DM） patients with functional astriction and diarrhea.Methods Gastrointestinal transit time（GITT） of 173 cases of diabetes mellitus complicated with constipation and diarrhea were measured,orocecal through time（OCTT） of wich were also measured by lactulose hydrogen breath test（LHBT）.Results The OCTT of the diabetes patients with constipation were（114.7±19.6） h;the anormaly accounted 27.1%（28/103）,the time of extension was accounted 18.4%（19/103）,shortening accounted 8.7%（9/103）.Constipation was classified as right colon inertia,left colon inertia,outlet obstrunction and total colon inertia according to the delayed segment of colon.The OCTT of the diabetes patients with diarrhea were（110.5±15.6） h;the anormaly accounted 22.8%（16/70）,the time of extension were 10 cases,shortening were 6 cases.The anormaly of TGITT in diabetes patients accounted 67.05%（116/173）.The anormaly of colon transit time accounted 33.53%（58/173）.Conclusion GITT measurement was important in diagnosis and classification,it has clinical values in the evaluation of treatment in constipation and diarrhea of the patients with diabetes.

关 键 词：胃肠通过时间 胃肠功能紊乱 糖尿病 

分 类 号：R587.1[医药卫生—内分泌]