沿海产盐区与非产盐区18～45岁人群碘营养状况及甲状腺功能水平研究  

Analysis on iodine nutritional status and thyroid functional level of population aged 18～45 in coastal salt-producing areas and coastal non-salt-producing areas in Xiamen city

作　　者：伍啸青[1,2,3] 陈志辉[4] 戴龙[1,2,3] 张亚平[1,2,3] 牛建军[1,2,3] 陈敏[1,2,3] 康天偿 邱志敏 柯金炼 郑立星 王木华[4] 张燕峰[1] 洪清祺[1] 吴佳妮[4] 林靖芸[7] 

机构地区：[1]厦门市疾病预防控制中心,福建361021 [2]福建医科大学预防医学专业教学基地 [3]厦门大学医学院预防医学教学基地 [4]福建省疾病预防控制中心 [5]厦门市翔安区疾病预防控制中心 [6]厦门市集美区疾病预防控制中心 [7]福建医科大学公共卫生学院

出　　处：《中国地方病防治》2012年第4期254-257,261,共5页Chinese Journal of Control of Endemic Diseases

基　　金：福建省医学创新课题(No:2009-CXB-68)

摘　　要：目的掌握厦门市沿海产盐区与非产盐区居民盐碘、18～45岁人群碘营养和甲状腺功能水平状况,为采取针对性的防治措施提供依据。方法选择沿海产盐区翔安区和非产盐区集美区为调查点,调查居民合格碘盐食用率、18～45岁育龄期妇女和男性尿碘水平、甲状腺激素水平和海带、紫菜的摄入习惯。结果产盐区和非产盐区盐碘中位数均为27.21 mg/kg,合格碘盐食用率分别为95.33%和96.33%;18～45岁男性尿碘中位数分别为206.55μg/L和232.95μg/L,尿碘<100μg/L的比例分别为20.97%和10%;18～45岁育龄期妇女尿碘中位数分别为176.95μg/L和227.70μg/L,尿碘<100μg/L的比例分别为21.67%和25%;产盐区和非产盐区18～45岁男性和育龄期妇女的甲状腺激素TSH、Tg、FT3、FT4、TPOAb、TT3、TT4中位数均在正常值范围内;产盐区18～45岁男性的甲状腺功能亢进阳性率为3.4%、育龄期妇女的甲状腺功能减退和亚临床甲状腺减退症的阳性率均为1.67%,而非产盐区均为0。产盐区和非产盐区18～45岁男性和育龄期妇女中均有一定比例易患甲状腺免疫性疾病的人群。每月食用海带、紫菜的次数≥4次、1～3次和<1次的人尿碘组间比较无统计学差异。结论产盐区和非产盐区18～45岁男性和育龄期妇女碘营养总体处于适宜状态,应坚持食盐加碘措施,对育龄期妇女在婚前体检时开展常规碘营养水平和甲状腺功能检测。Objective To identify the status of iodine content in edible salt, the iodine nutritional status and thyroid function of population aged 18 -45 in coastal salt- producing areas and coastal non -salt -producing areas in Xiamen city, and provide the evidence for establishing the strategy of IDD control. Method Xiang＇ an salt - producing areas and Ji＇ mei non - salt - producing areas were selected as research spots. The proportion of households using adequate iodized salt, urine - iodine, blood thyroid hor- mone levels, kelp and seaweed intake habits of population among subjects aged 18 -45 were investigated. Results The medians of salt iodine of coastal salt - producing areas and coastal non - salt - producing areas were 27.21 mg/kg; the edible qualified iodina- ted salt rate of the two areas were 96.33% and 95.33% respectively; Among men aged 18 -45, the median of urinary iodine were 232.95 μg,/L and 206.55 μg/L respectively, the proportion of urine - iodine level 〈 100 μg/L were 20.97% and 10% ; Among women aged 18 to 45, the median of urinary iodine were 227.70 μg/L and 176.95μg,/L respectively, the proportion of urine - io- dine level 〈 100 μg/L were 21.67% and 25%. All the medians of thyroid hormones including TSH, TG, FT3, FT4, TPOAb, TT3 and TT4 of population aged 18-45 in coastal salt -producing areas and coastal non -salt -producing areas were in normal ranges; The rate of hyperthyroidism of men aged 18 -45 in coastal salt - producing areas was 3.4%, the rate of hypothyroidism and subclinical hypothyroidism of women of reproductive age were both 1.67%, while the rate of coastal non - salt - producing areas were none. In every group, there was a certain proportion of susceptible population who was identified with autoimmune thyroid diseases. The me- dian of urinary iodine of people who intake of sea - tangle and sea - sedge with frequency of great than or equal to 4, among 1 - 3 and less than 1 were no statistically significant difference. Conclusion The men aged 18 -45 and women of reproducti

关 键 词：碘 育龄期妇女 18~45岁男性 碘营养水平 甲状腺功能 

分 类 号：R591.1[医药卫生—内科学]