慢性肾病对冠状动脉慢性完全闭塞病变侧支循环形成的影响  

Effect of chronic kidney disease on the formation of coronary collateral vessels in patients with coronary chronic total occlusion

作　　者：荆亚军[1] 朱劲舟[1] 张瑞岩[1] 

机构地区：[1]上海交通大学医学院附属瑞金医院心内科,200025

出　　处：《介入放射学杂志》2012年第8期617-620,共4页Journal of Interventional Radiology

摘　　要：目的探讨慢性肾病是否为冠状动脉慢性完全闭塞病变(CTO)侧支循环形成不良的独立预测因素。方法 2003年1月至2011年10月收治125例经冠状动脉造影确诊为CTO患者。运用Rentrop评分系统将患者分为有侧支循环组(99例)和无侧支循环组(26例);并用多因素Logistic回归分析校正混杂因素。结果多因素Logistic回归分析表明,慢性肾病是CTO侧支循环形成不良的独立预测因素(OR=5.22,P=0.021)。结论合并慢性肾病的CTO患者冠状动脉侧支循环形成不良的相对危险是不合并慢性肾病患者的5.22倍。Objective To investigate whether chronic kidney disease is an independent predictor for the development of coronary collateral vessels in patients with coronary chronic total occlusion. Methods During the period from Jan. 2003 to Oct. 2011, a total of 125 patients with angiography-confirmed coronary chronic total occlusion （CTO） were admitted to the hospital. Using Rentrop scoring system, the patients were divided into good collateral circulation group （n = 99） and poor collateral circulation group （n = 26）. Confounding factors were adjusted by multivariate logistic regression analysis. Results Multivariate logistic regression analysis indicated that chronic kidney disease was an independent predictor for the development of coronary collateral circulation in patients with CTO. Conclusion The relative risk of poor collateral circulation formation in CTO patients complicated by chronic kidney disease is 5.22 times higher than that in CTO patients having no chronic kidney disease.

关 键 词：慢性肾病 冠状动脉慢性完全阻塞性病变 侧支循环 

分 类 号：R692[医药卫生—泌尿科学] R54[医药卫生—外科学]